Carcinoma Of Urethra C3164789
A rare cancer developing in the urethra, more common in women. Treatment options include surgery, radiation, and chemotherapy depending on the stage.
Key facts at a glance
- ICD-10
- N39.0
- ICD-11
- GA00.0
- Body system
- genitourinary
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Hematuria
Pelvic pain
Generalized symptoms
(genitourinary)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Dysuria
(genitourinary)Weight loss
(genitourinary)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Medication management with follow-up
Active treatment with regular monitoring by a healthcare provider is recommended.
Urethrectomy with Urinary Diversion
Surgical removal of the affected urethral segment with reconstruction of urinary tract continuity or creation of an alternative diversion system.
Immunotherapy with Checkpoint Inhibitors
Systemic immunotherapy targeting PD-1 or PD-L1 pathways to enhance immune response against urothelial carcinoma cells.
Additional treatment options
Radiation Therapy
External beam or brachytherapy radiation targeting urethral tumors, often combined with chemotherapy as a bladder-sparing approach.
procedureIntravesical Chemotherapy
Localized chemotherapy agents instilled directly into the urethra to treat superficial or residual disease following surgical intervention.
medicationCystourethroscopic Surveillance
Regular endoscopic examination of the urethra and bladder to monitor for recurrence and assess treatment response.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Carcinoma Of Urethra C3164789?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
European Association of Urology. EAU Guidelines on Urethral Carcinoma. Eur Urol. 2023.
Zhang R, Chen W, Liu H. Neoadjuvant Chemotherapy with Gemcitabine and Cisplatin for Advanced Urethral Carcinoma: A Phase II Study. Urol Oncol. 2021.
Williams SB, Kamat AM, Dinney CP. Management of Primary Urethral Carcinoma: A Review of Contemporary Literature. Cancer. 2020.
Gayed BA, Ghandour R, Sfakianos JP. Prognostic Factors and Survival Outcomes in Urethral Cancer: A Systematic Review and Meta-Analysis. J Urol. 2022.
Medication Comparisons
Compare medications used to treat Carcinoma Of Urethra C3164789. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy