Catecholaminergic Polymorphic Ventricular Tachycardia 3 C3151463
A genetic heart rhythm disorder causing dangerously fast heartbeats during exercise or emotional stress. It affects individuals with inherited mutations, often diagnosed in childhood or adolescence. Treatment includes medications, activity restrictions, and sometimes implanted devices to control heart rhythm.
Key facts at a glance
- ICD-10
- I78.0
- ICD-11
- BA00.0
- Body system
- cardiovascular
- Severity
- critical
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Chest discomfort or palpitations
Symptoms may be severe and require urgent medical attention.
Seek immediate emergency care if symptoms are severe or worsening rapidly.
Exercise-induced syncope
Ventricular tachycardia during physical activity
Dizziness with emotional stress
Palpitations at rest
Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Beta-Blocker Therapy
High-dose beta-blockers form the cornerstone of CPVT treatment, significantly reducing catecholamine-triggered arrhythmias by blocking sympathetic stimulation.
Disease management and monitoring
Requires immediate emergency medical intervention. Do not delay treatment.
Flecainide Adjunctive Therapy
Class IC antiarrhythmic flecainide added to beta-blocker therapy reduces ventricular ectopic beats and bidirectional tachycardia in CPVT patients.
Additional treatment options
Implantable Cardioverter-Defibrillator (ICD)
ICD implantation for patients with breakthrough cardiac events despite optimal medical therapy, providing life-saving defibrillation for ventricular fibrillation.
surgicalExercise Restriction
Significant limitation or avoidance of strenuous exercise and competitive sports, as physical exertion is the primary trigger for arrhythmias in CPVT.
lifestyleLeft Cardiac Sympathetic Denervation
Surgical removal of the lower portion of the left stellate ganglion to reduce norepinephrine release and prevent stress-induced arrhythmias.
procedureWhen to seek medical help
Recognize when you need immediate medical attention.
Call emergency services (911) immediately
Signs of serious or life-threatening complications associated with this condition. Immediate medical evaluation is required.
Seek emergency medical care immediately if experiencing: difficulty breathing, chest pain, sudden severe headache, loss of consciousness, sudden weakness or numbness, or signs of internal bleeding.
Frequently asked questions
Common questions about this topic.
What is Catecholaminergic Polymorphic Ventricular Tachycardia 3 C3151463?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Priori SG, Blom NA, Brugada J, et al. 2022 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death. Eur Heart J. 2022;43(40):3997-4126.
Liu JF, Jaleel A, Antzelevitch C. Catecholaminergic Polymorphic Ventricular Tachycardia: Mechanisms and Management. Circ Arrhythm Electrophysiol. 2020;13(5):e008200.
Roston TM, Vinocur JM, Maginot KR, et al. Clinical Course of Catecholaminergic Polymorphic Ventricular Tachycardia in Children: A Multicenter Prospective Study. J Am Coll Cardiol. 2021;78(1):22-34.
Wilde AAM, Amin AS, Ackerman MJ. Calmodulin mutations and catecholaminergic polymorphic ventricular tachycardia: Clinical and functional aspects. Heart Rhythm. 2019;16(11):1659-1665.
Medication Comparisons
Compare medications used to treat Catecholaminergic Polymorphic Ventricular Tachycardia 3 C3151463. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy