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Cerebral Cavernous Malformation 1 C1366911

Published: July 22, 2026Updated: August 25, 2026

A vascular malformation made up of clusters of abnormal blood vessels in the brain that can bleed or cause seizures. May be inherited or occur sporadically. Treatment ranges from monitoring to surgical removal depending on symptoms.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

ICD-10
G40.909
ICD-11
8A00.0
Body system
neurologic
Severity
moderate
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Warning signs - seek immediate care

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Headache

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Seizures

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Intracranial hemorrhage

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Focal neurological deficits

Generalized symptoms

(neurologic)

Noticeable symptoms that may vary in intensity over time.

Frequency: Common at all stages

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Dietary counseling and physical activity plan

Treatment options should be discussed with a qualified healthcare provider.

lifestyle
2

Regular MRI Surveillance

Periodic magnetic resonance imaging to monitor lesion size, location, and any changes in cavernous malformations. Helps guide treatment decisions and assess risk of hemorrhage or neurological symptoms.

monitoring
3

Seizure Management with Anticonvulsants

When seizures occur, appropriate anticonvulsant medication is initiated with careful titration based on seizure type, patient age, and comorbidities. Regular monitoring ensures therapeutic levels and manages side effects.

medication

Additional treatment options

Surgical Resection

Microsurgical removal of symptomatic cavernous malformations, particularly those causing hemorrhage, progressive neurological deficits, or refractory seizures. Surgery aims for complete excision while minimizing surrounding brain tissue damage.

surgical

Stereotactic Radiosurgery

Focused radiation therapy targeting cavernous malformations to reduce re-hemorrhage risk, particularly for deep or eloquent area lesions where open surgery carries high morbidity.

procedure

Activity Modification and Risk Reduction

Counseling on avoiding activities with high trauma risk, controlling blood pressure, and minimizing anticoagulant use when possible. Education on warning signs requiring immediate medical attention.

lifestyle

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Cerebral Cavernous Malformation 1 C1366911?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Akers AL, Johnson CA, Steinberg GK, et al. Updated United States guidelines for the diagnosis and treatment of cerebral cavernous malformations. Stroke. 2021.

guideline2021
2

Mouchtouris N, Chalouhi N, Tjoumakaris S, et al. Management of cerebral cavernous malformations: a review. Neurosurgery. 2020.

review2020
3

Shenkar R, Girard R, Li H, et al. Novel approach to therapeutic targeting of cerebral cavernous malformation using statin therapy. J Cereb Blood Flow Metab. 2019.

clinical_trial2019
4

Ding D, Starke RM, Kano H, et al. Stereotactic radiosurgery for cerebral cavernous malformations: a meta-analysis. J Neurosurg. 2018.

meta_analysis2018

Medication Comparisons

Compare medications used to treat Cerebral Cavernous Malformation 1 C1366911. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy