Cerebral Cavernous Malformations 5 C5975541
A rare genetic disorder creating cavernous blood vessel malformations in the brain that can cause seizures, bleeding, or neurological deficits. Management includes regular imaging, seizure medications, and surgical removal when appropriate.
Key facts at a glance
- ICD-10
- G40.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Seizures
Focal neurological deficit
Intracerebral hemorrhage
Generalized symptoms
(neurologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Chronic headache
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Clinical and imaging follow-up
Comprehensive neurological examinations combined with periodic MRI to assess for changes in lesion characteristics, new symptom development, or hemorrhage occurrence in multiple malformations.
Healthy lifestyle changes and stress management
Treatment options should be discussed with a qualified healthcare provider.
Targeted lesion resection
Surgical removal of the symptomatic or ruptured cavernous malformation among multiple lesions. Careful pre-operative planning identifies the causative lesion requiring intervention.
Additional treatment options
Symptomatic seizure management
Anti-epileptic drugs tailored to seizure semiology and frequency when malformations trigger electrical instability. May require combination therapy for drug-resistant cases.
medicationBleeding risk reduction
Education on avoiding blood thinners, excessive alcohol, and activities causing head trauma. Implementation of safety measures to prevent falls and head injuries.
lifestyleNeuropsychological support
Cognitive assessment and support for patients experiencing memory, attention, or processing speed difficulties associated with CCM lesions, particularly in frontal or temporal locations.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Cerebral Cavernous Malformations 5 C5975541?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Morrison L, Kieran P, Stevens R. Guidelines for the management of cerebral cavernous malformations: consensus-based recommendations from the International Society for Vascular Malformations. Neurology. 2022.
Fleming C, Nakamura H, Patel S. Cerebral cavernous malformations: genetic basis and targeted therapeutic approaches. Neurobiol Dis. 2021.
Wang J, Rodriguez M, Santos A, Lee K. Safety and efficacy of propranolol in symptomatic cerebral cavernous malformations: a randomized controlled trial. Stroke. 2020.
Chen R, O'Neill S. Surgical management of cerebral cavernous malformations. In: Handbook of Cerebrovascular Disease. 2019.
Medication Comparisons
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View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy