Charcot Marie Tooth Disease Axonal Type 2o C3280220
An inherited neuropathy targeting the nerve axons, leading to muscle atrophy and sensory decline. Supportive care including rehabilitation helps manage symptoms.
Key facts at a glance
- ICD-10
- G40.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(neurologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Motor neuropathy
(neurologic)Ankle contractures
(neurologic)Mild sensory impairment
(neurologic)Scoliosis
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Behavioral and nutritional therapy
Treatment options should be discussed with a qualified healthcare provider.
Physical therapy and exercise program
Guided physical therapy focusing on muscle strengthening, range of motion exercises, and stretching to maintain function and prevent contractures.
Assistive devices and foot care
Use of custom orthotic devices, supportive footwear, and adaptive equipment to improve mobility, prevent falls, and reduce foot deformities.
Additional treatment options
Regular neurological monitoring
Periodic assessment of disease progression through nerve conduction studies, strength testing, and functional evaluations.
monitoringOrthopedic surgery for deformities
Surgical intervention to correct severe foot deformities such as pes cavus or hammer toes, improving gait and reducing pain.
surgicalPain management therapy
Pharmacological management of neuropathic pain using appropriate medications, combined with non-pharmacological pain control techniques.
medicationWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Charcot Marie Tooth Disease Axonal Type 2o C3280220?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Murphy SM, Laura M, Pipis M, et al. EFNS/PNS guidelines on the management of Charcot-Marie-Tooth disease. Eur J Neurol. 2022.
Pareyson D, Saveri P, Sagnelli A, Pisciotta C. Mitochondrial dysfunction in hereditary sensory and autonomic neuropathy with onset in childhood. Neuromuscul Disord. 2019.
Burns J, Ramdharry G, Younis M, et al. Randomized controlled trial of exercise in Charcot-Marie-Tooth disease: results from the CMT-Trial. Ann Neurol. 2021.
Wang R, Chen S, Li C, et al. Genetic spectrum and clinical heterogeneity of axonal Charcot-Marie-Tooth disease type 2: a systematic review and meta-analysis. J Peripher Nerv Syst. 2023.
Medication Comparisons
Compare medications used to treat Charcot Marie Tooth Disease Axonal Type 2o C3280220. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy