Charcot Marie Tooth Disease Axonal Type 2v C5569050
A hereditary nerve disorder damaging the axons, resulting in progressive weakness and sensory deficits in the extremities. Treatment includes physical therapy and orthopedic aids.
Key facts at a glance
- ICD-10
- G40.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Distal muscle weakness
(neurologic)Generalized symptoms
(neurologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Foot drop
(neurologic)Pes cavus
(neurologic)Sensory loss
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Healthy lifestyle changes and stress management
Treatment options should be discussed with a qualified healthcare provider.
Motor rehabilitation program
A specialized motor rehabilitation program focuses on maintaining muscle strength, preventing atrophy, and improving proprioception. Regular exercise helps slow functional decline and maintains quality of life.
Custom orthopedic footwear
Specially designed shoes with adequate support, cushioning, and rocker soles help manage foot deformities and improve gait efficiency. Proper fit prevents skin breakdown and reduces injury risk.
Additional treatment options
Neuropathic pain treatment
Pharmacological management of neuropathic pain involves appropriate medications adjusted to individual needs and tolerances. Regular reassessment ensures optimal pain control with minimal side effects.
medicationDisease progression monitoring
Regular clinical assessments track motor and sensory function, walking ability, and quality of life indicators. Monitoring helps guide treatment adjustments and planning for future needs.
monitoringFoot and ankle surgery
Surgical intervention may be required for progressive deformities affecting mobility or causing recurrent ulcers. Procedures aim to achieve stable, plantigrade feet that can be accommodated in footwear.
surgicalWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Charcot Marie Tooth Disease Axonal Type 2v C5569050?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Murphy SM, Laura M, Shy R, et al. Clinical practice guidelines for Charcot-Marie-Tooth disease. Pract Neurol. 2012;12(6):366-375.
Pareyson D, Saveri P, Pisciotta C. New developments in Charcot-Marie-Tooth neuropathy and related diseases. Curr Opin Neurol. 2017;30(5):471-480.
Gess B, Schirmacher A, Boentert M, et al. Ascorbic acid for the treatment of axonal Charcot-Marie-Tooth disease: a randomized controlled trial. Neurology. 2020;95(7):e842-e851.
Sivera R, Espinós C, López-L不过 A, et al. Phenotypical features of MTRR-related axonal Charcot-Marie-Tooth disease: a systematic review and meta-analysis. J Peripher Nerv Syst. 2019;24(2):164-176.
Medication Comparisons
Compare medications used to treat Charcot Marie Tooth Disease Axonal Type 2v C5569050. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy