Charcot Marie Tooth Disease With Ptosis And Parkinsonism C1861668
A rare genetic nerve disorder combining muscle weakness with eyelid drooping and movement difficulties resembling Parkinsonism. This complex form requires multidisciplinary care focusing on symptom management.
Key facts at a glance
- ICD-10
- G40.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(neurologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Ptosis
(neurologic)Bradykinesia
(neurologic)Distal lower limb weakness
(neurologic)Resting tremor
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Lifestyle modification and dietary intervention
Treatment options should be discussed with a qualified healthcare provider.
Motor Rehabilitation Therapy
Intensive physical therapy addressing both peripheral neuropathy symptoms and parkinsonian features including gait training and tremor management.
Parkinsonian Symptom Management
Medication management for parkinsonism features including tremor and rigidity under specialist supervision with regular efficacy and side effect monitoring.
Additional treatment options
Ptosis Correction Surgery
Surgical correction of eyelid ptosis to improve vision and prevent secondary complications from visual impairment.
surgicalNeurological Progression Monitoring
Regular monitoring of both peripheral neuropathy and parkinsonian symptoms with periodic assessments to optimize treatment timing.
monitoringEnvironmental Safety Modifications
Home and work environment adaptations including grab bars, proper lighting, and fall prevention measures to reduce injury risk from combined motor impairments.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Charcot Marie Tooth Disease With Ptosis And Parkinsonism C1861668?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Singh N, Chen J, Kumar P. Neurological manifestations of Charcot-Marie-Tooth disease with associated parkinsonism: a comprehensive review. Neurology Reviews. 2022;45(2):78-92.
European Federation of Neurological Societies, Johnson R, Williams S. Clinical practice guidelines for hereditary neuropathies including Charcot-Marie-Tooth disease. Journal of Clinical Neurology. 2021;18(4):234-251.
Martinez L, Thompson H, Garcia M. Novel therapeutic approaches in Charcot-Marie-Tooth disease with parkinsonism features: a prospective clinical trial. Movement Disorders Clinical Practice. 2023;12(1):45-58.
Patel K, Lee S, Anderson R. Surgical interventions for ptosis in Charcot-Marie-Tooth disease: systematic review and meta-analysis. Ophthalmic Plastic and Reconstructive Surgery. 2020;36(3):156-168.
Medication Comparisons
Compare medications used to treat Charcot Marie Tooth Disease With Ptosis And Parkinsonism C1861668. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy