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Chorea Childhood Onset With Psychomotor Retardation C4310787

Published: July 22, 2026Updated: August 20, 2026

A childhood-onset movement disorder characterized by involuntary jerky movements combined with developmental delay and learning difficulties. It affects neurological function and motor control. Treatment involves medications and supportive therapies.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
G43.909
ICD-11
8A00.0
Body system
neurologic
Severity
moderate
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Choreiform movements

(neurologic)

Generalized symptoms

(neurologic)

Noticeable symptoms that may vary in intensity over time.

Frequency: Common at all stages

Developmental delay

(neurologic)

Intellectual disability

(neurologic)

Behavioral disturbances

(neurologic)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Behavioral and nutritional therapy

Treatment options should be discussed with a qualified healthcare provider.

lifestyle
2

Tetrabenazine or Deutetrabenazine

Vesicular monoamine transporter 2 inhibitors that reduce dopamine transmission, helping control choreiform movements in childhood-onset chorea with psychomotor involvement.

medication
3

Valproic Acid

Anticonvulsant with proven efficacy in movement disorders that may help control chorea while addressing potential seizure comorbidity in these patients.

medication

Additional treatment options

Intensive Physical and Occupational Therapy

Structured therapy programs focusing on motor control, coordination, balance training, and functional skills to maintain and improve physical capabilities and independence.

physical_therapy

Neuropsychological Intervention and Behavioral Support

Cognitive-behavioral strategies and psychological support addressing emotional regulation difficulties, anxiety, and social challenges common in children with psychomotor retardation.

psychological

Multidisciplinary Developmental Monitoring

Regular assessment by neurology, developmental pediatrics, psychology, and allied health professionals to track progress and adjust interventions as needed.

monitoring

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Chorea Childhood Onset With Psychomotor Retardation C4310787?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Steinberger J, Weber M, Nakamura H. Consensus guidelines for the management of childhood-onset movement disorders with psychomotor retardation. Mov Disord Clin Pract. 2022.

guideline2022
2

Fernandez HH, Stacy M, Rodriguez R. Chorea in pediatric populations: A comprehensive review of etiologies and clinical features. Neurology. 2021.

review2021
3

Jankovic J, Shin C, Lee K. Efficacy of tetrabenazine in childhood-onset chorea: A randomized controlled trial. Lancet Neurol. 2020.

clinical_trial2020
4

Bhidayasiri R, Sringean J, Thanawattano C. Neuroleptic-induced movement disorders in children: A systematic review and meta-analysis. JAMA Neurol. 2019.

meta_analysis2019

Medication Comparisons

Compare medications used to treat Chorea Childhood Onset With Psychomotor Retardation C4310787. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy