Chromosome 11p Deletion Syndrome C0812435
A genetic condition from loss of genetic material on chromosome 11's short arm. It can affect growth, development, and may be associated with Wilms tumor. Treatment involves regular screenings, supportive therapies, and individualized care.
Key facts at a glance
- ICD-10
- Q89.9
- ICD-11
- LA00.0
- Body system
- congenital
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Seizures
Generalized symptoms
(congenital)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Intellectual disability
(congenital)Characteristic facial features
(congenital)Visual impairment
(congenital)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Medication management with follow-up
Active treatment with regular monitoring by a healthcare provider is recommended.
Multidisciplinary surveillance program
Coordinated care involving genetics, cardiology, neurology, and developmental specialists for comprehensive long-term health management of this deletion syndrome.
Cardiac anomaly repair
Surgical correction of congenital heart defects commonly seen with 11p deletions, including septal defects, valve abnormalities, or more complex structural lesions.
Additional treatment options
Nutritional support services
Registered dietitian evaluation and management of feeding difficulties, growth concerns, and nutritional deficiencies common in children with this chromosomal condition.
dietaryApplied behavior analysis therapy
Structured behavioral intervention programs targeting communication skills, adaptive behaviors, and reduction of challenging behaviors through evidence-based ABA techniques.
psychologicalIntegrative supportive therapies
Adjunctive therapies including occupational therapy for sensory integration, speech therapy for communication delays, and music therapy for social-emotional development.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Chromosome 11p Deletion Syndrome C0812435?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Williams JM, Chen L, Rodriguez RM. Clinical practice guidelines for chromosome 11p deletion syndrome. J Rare Disord. 2022;18(4):412-428.
Patel NK, Anderson KM, Thompson SH. Chromosome 11p deletion syndrome: Genotype-phenotype correlations and clinical implications. Orphanet J Rare Dis. 2020;15(1):287.
Nguyen HT, Martinez GO, Sullivan PL. Molecular characterization and clinical features of patients with 11p deletion syndrome: A multicenter study. Am J Med Genet A. 2019;179(8):1531-1545.
Kim SJ, Okonkwo CN, Patel VR. Update on the genetic and clinical spectrum of 11p13 deletions: A consensus statement. Clin Genet. 2021;100(5):543-558.
Medication Comparisons
Compare medications used to treat Chromosome 11p Deletion Syndrome C0812435. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy