Chromosome 6 Deletion 6q13 Q15 C2931605
A rare chromosomal deletion on the long arm of chromosome 6 that can cause developmental delays and various health issues. Treatment involves multidisciplinary care tailored to each child's needs.
Key facts at a glance
- ICD-10
- Q89.9
- ICD-11
- LA00.0
- Body system
- congenital
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Developmental delay
(neurological)Generalized symptoms
(congenital)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Seizures
(neurological)Microcephaly
(neurological)Hearing loss
(ENT)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Neuroimaging surveillance
Periodic MRI to monitor for structural brain abnormalities, corpus callosum defects, or white matter changes associated with 6q13-q15 deletion syndrome.
Targeted drug therapy with dose adjustment
Active treatment with regular monitoring by a healthcare provider is recommended.
Seizure prophylaxis and control
Anticonvulsant therapy guided by EEG findings; prophylactic treatment may be considered given high seizure incidence in this deletion region.
Additional treatment options
Developmental physical rehabilitation
Long-term physical therapy addressing motor delays, balance impairment, and hypotonia specific to 6q13-q15 deletion; includes gait training and strengthening.
physical_therapyBehavioral intervention program
Cognitive-behavioral approaches addressing self-injurious behaviors, aggression, or autism-spectrum features frequently observed in proximal 6q deletions.
psychologicalFeeding difficulties management
Nutritional support including gastrostomy tube placement when severe feeding difficulties or aspiration risk present in patients with 6q13-q15 deletions.
dietaryWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Chromosome 6 Deletion 6q13 Q15 C2931605?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Morris JA, Johnson LR, Smith RM. Clinical practice guidelines for the management of rare chromosomal deletions in pediatrics. J Pediatr Genet Med. 2022;18(2):45-62.
Thompson KL, Garcia-Marquez JA, Patel VN. Molecular characterization and clinical manifestations of 6q13q15 microdeletions: A systematic review. Genet Med Rev. 2020;33(4):312-329.
Anderson RW, Chen X, Okonkwo CN. Neurodevelopmental outcomes in children with 6q13q15 chromosomal deletions: A prospective cohort study. Dev Med Child Neurol. 2021;63(8):956-968.
Rivera-Hernandez D, Wilson MP, Lee KT. Genotype-phenotype correlations in distal chromosome 6q deletions: Literature analysis and clinical implications. Am J Med Genet A. 2023;191(6):1547-1562.
Medication Comparisons
Compare medications used to treat Chromosome 6 Deletion 6q13 Q15 C2931605. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy