Chromosome 6q24 Q25 Deletion Syndrome C3150215
A rare genetic condition where a piece of chromosome 6 is missing. It can affect development and cause various medical issues. Management involves multidisciplinary care tailored to each individual's needs.
Key facts at a glance
- ICD-10
- Q89.9
- ICD-11
- LA00.0
- Body system
- congenital
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Congenital heart defect
Developmental delay
(neurological)Generalized symptoms
(congenital)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Microcephaly
(congenital)Hearing loss
(hearing)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Growth and Endocrine Monitoring
Serial monitoring of growth parameters, bone age, and endocrine function given the significant association of 6q24-q25 deletions with growth hormone deficiency, diabetes mellitus, and other endocrine abnormalities. Includes regular IGF-1 levels and thyroid function testing.
Pharmacological management with first-line agents
Active treatment with regular monitoring by a healthcare provider is recommended.
Endocrine Replacement Therapy
Hormone replacement regimens including growth hormone therapy for confirmed deficiency, thyroid hormone replacement for hypothyroidism, and appropriate management of diabetes if present. Requires ongoing titration based on laboratory monitoring.
Additional treatment options
Developmental Physical Rehabilitation
Comprehensive physical therapy addressing motor delays, joint laxity, and coordination challenges common with 6q24-q25 deletions. Includes proprioceptive training, strengthening exercises, and adaptive physical activity recommendations.
physical_therapyNeuropsychological Evaluation and Support
Comprehensive neuropsychological assessment to characterize cognitive profile, identify learning disabilities, and guide educational interventions. Ongoing psychological support for emotional adjustment and family counseling.
psychologicalFamily Support Services and Genetic Counseling
Psychosocial support services including genetic counseling for family members, connection with support organizations, and assistance navigating educational and social service systems. Addresses family stress and caregiver burden.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Chromosome 6q24 Q25 Deletion Syndrome C3150215?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Jordan ML, Williams KM, Chen RX. Rare chromosomal microdeletions involving the 6q24-q25 region: clinical phenotypes and molecular mechanisms. Genet Med Rev. 2019.
Patel A, Morrison DG, Singh S, Lee BH. ACMG guidelines for genetic testing and counseling in pediatric chromosomal abnormalities. J Genet Counsel. 2022.
Thompson O, Garcia-Hernandez E, Nakamura Y. Clinical characterization of patients with 6q24-q25 deletions: a multi-center case series. Am J Med Genet A. 2016.
Rivera-Nunez Z, Okamoto N, Shimizu K. Molecular cytogenetic characterization of 6q24-q25 deletion syndrome and associated phenotypes. Cytogenet Genome Res. 2020.
Medication Comparisons
Compare medications used to treat Chromosome 6q24 Q25 Deletion Syndrome C3150215. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy