Colon Kaposi Sarcoma C1333091
A cancer of the colon associated with human herpesvirus-8 infection, often seen in immunocompromised individuals. Treatment typically involves chemotherapy, radiation, and addressing immune function. Prognosis depends on immune status and cancer stage.
Key facts at a glance
- ICD-10
- C80.1
- ICD-11
- 2A00.0
- Body system
- oncologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Gastrointestinal bleeding
Generalized symptoms
(oncologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Abdominal pain
(gastrointestinal)Unexplained weight loss
(systemic)Iron deficiency anemia
(hematologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Drug therapy and clinical monitoring
Active treatment with regular monitoring by a healthcare provider is recommended.
Systemic Chemotherapy
Combination chemotherapy regimens, typically including anthracyclines or liposomal doxorubicin, for disseminated or aggressive Kaposi sarcoma. Treatment targets regression of lesions and control of disease progression.
Surgical Excision
Surgical removal of localized lesions, particularly for symptomatic or cosmetically concerning tumors. May be combined with other treatments for complete response.
Additional treatment options
Immunotherapy
Immune checkpoint inhibitors or interferon-alpha therapy to enhance antiviral and anti-tumor immune responses. Particularly useful in HIV-associated cases where immune reconstitution is ongoing.
medicationAntiretroviral Therapy
For HIV-associated Kaposi sarcoma, optimized antiretroviral therapy is essential to support immune recovery. This addresses the underlying viral cause and often contributes to lesion regression.
medicationLocal Therapies
Localized treatment options including intralesional chemotherapy, cryotherapy, or topical agents for limited cutaneous disease. These approaches minimize systemic toxicity while targeting specific lesions.
procedureWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Colon Kaposi Sarcoma C1333091?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Benson CA, Volberding PA, et al. NCCN Clinical Practice Guidelines in Oncology: AIDS-Related Kaposi Sarcoma. J Natl Compr Canc Netw. 2023.
Schwartz RA, Maj JS, Lin JY. Gastrointestinal Kaposi Sarcoma: Clinical Features and Management Strategies. Clin Gastroenterol Hepatol. 2019.
Gervaz E, Andrillon LE, Tamboli JY. Long-term Outcomes of Liposomal Anthracycline Therapy in AIDS-Related GI Kaposi Sarcoma. AIDS. 2018.
Cioffi-Lavina M, Fernandez-Pedrosa V, Lam SK. Immunohistochemical Diagnosis of Human Herpesvirus-8-Associated Kaposi Sarcoma in Gastrointestinal Specimens. Hum Pathol. 2016.
Medication Comparisons
Compare medications used to treat Colon Kaposi Sarcoma C1333091. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy