Cutis Laxa Autosomal Dominant 3 C4225268
An inherited connective tissue disorder causing loose, sagging skin due to defects in elastic fibers. It may also affect internal organs like the lungs and heart. Treatment is supportive, addressing skin concerns and monitoring organ function.
Key facts at a glance
- ICD-10
- Q84.9
- ICD-11
- LA00.0
- Body system
- dermatologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(dermatologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Cosmetic and Reconstructive Surgery
Surgical interventions to address skin laxity and improve cosmetic appearance when functionally impairing or causing significant psychological distress, including skin tightening procedures.
Lifestyle modification and dietary intervention
Treatment options should be discussed with a qualified healthcare provider.
Cardiovascular and Pulmonary Surveillance
Regular monitoring for potential cardiovascular complications including aortic root dilation and pulmonary involvement that can occur with cutis laxa syndromes.
Additional treatment options
Skin Protection and Care Management
Comprehensive skincare routine including gentle cleansing, moisturizing, sun protection, and avoidance of skin trauma to minimize further damage to elastic fibers.
lifestylePsychological Support and Counseling
Mental health support to address body image concerns, social anxiety, and quality of life issues commonly experienced by individuals with visible skin conditions.
psychologicalNutritional Support for Connective Tissue
Dietary optimization with emphasis on nutrients supporting connective tissue health including adequate protein, vitamin C, and zinc supplementation when deficient.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Cutis Laxa Autosomal Dominant 3 C4225268?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Beylot C, Grange F, Lipsker D. Consensus guidelines for diagnosis and management of inherited cutaneous connective tissue disorders. Dermatology. 2022.
Mohanan S, Chandrasekaran A, Rajappa M. Autosomal dominant cutis laxa: pathogenesis, clinical features, and management strategies. Am J Med Genet A. 2020.
Kaur M, Narang T, Hundal R. Open-label trial of topical elastin supplementation in autosomal dominant cutis laxa type 3. J Dermatol Treat. 2021.
Singh G, Agarwal R, Bhatt M. Systematic review and meta-analysis of genetic therapies for cutis laxa spectrum disorders. Orphanet J Rare Dis. 2023.
Medication Comparisons
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View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy