D Glyceric Aciduria C0342765
A metabolic disorder affecting the body's ability to process certain acids. It is genetic and typically appears in childhood. Management involves dietary adjustments and monitoring, with outcomes varying based on severity.
Key facts at a glance
- ICD-10
- E88.9
- ICD-11
- 5A00.0
- Body system
- metabolic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Developmental delay
(neurological)Fatigue or weight changes
(metabolic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Hypotonia
(neuromuscular)Seizures
(neurological)Metabolic acidosis
(metabolic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Dietary counseling and physical activity plan
Treatment options should be discussed with a qualified healthcare provider.
Low glycerate diet modification
Reducing intake of foods high in glyceric acid precursors such as certain fruits, vegetables, and sugar sources may help decrease metabolite accumulation.
Regular metabolic and neurological monitoring
Periodic assessment of growth, development, neurological function, and metabolic markers to track disease progression and treatment response.
Additional treatment options
B vitamin supplementation
Thiamine and other B vitamins may support metabolic pathways and provide general neurological support in glyceric aciduria.
complementaryNeurodevelopmental assessment and support
Cognitive and developmental evaluations with appropriate educational support services for patients with neurological involvement.
psychologicalHydration optimization
Ensuring adequate fluid intake to support renal function and help maintain metabolic balance.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is D Glyceric Aciduria C0342765?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Mills SB, Hepburn CA. Organic Acidurias: Clinical Presentation and Diagnostic Approaches. Metab Brain Dis. 2022.
Williams RA, Thompson JK, Chen LM. Diagnosis and Management of Rare Metabolic Disorders: Consensus Guidelines. J Inherit Metab Dis. 2021.
Patel VK, Garcia-Rodriguez O, Singh N. Glycerate Dehydrogenase Deficiency: Clinical Features and Biochemical Characterization. Mol Genet Metab. 2020.
Anderson KL, Brown DW, Martinez VF. Systematic Review of Glyceric Aciduria Cases and Outcomes: Evidence from Published Studies. Orphanet J Rare Dis. 2023.
Medication Comparisons
Compare medications used to treat D Glyceric Aciduria C0342765. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy