Debrisoquine Ultrarapid Metabolism Of C1837157
This genetic trait causes certain medications to break down faster than usual. It can reduce drug effectiveness or increase side effects. Doctors may adjust dosages based on genetic testing.
Key facts at a glance
- ICD-10
- E88.9
- ICD-11
- 5A00.0
- Body system
- metabolic
- Severity
- mild
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Confusion
Abnormally intense drug response
(general)Fatigue or weight changes
(metabolic)Mild symptoms that may not significantly impact daily life.
Frequency: Common at all stages
Orthostatic hypotension
(cardiovascular)Dizziness
(nervous system)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Cardiac Diagnostic Workup
Comprehensive evaluation including echocardiogram, stress testing, and potentially cardiac MRI to determine the underlying cause of the deep S wave finding.
Exercise prescription and weight management
Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.
Electrocardiogram Serial Monitoring
Regular ECG monitoring to track changes in the S wave pattern over time and correlate with symptoms or disease progression.
Additional treatment options
Underlying Condition Treatment
If the deep S wave indicates an underlying cardiac condition such as left ventricular hypertrophy, appropriate medications like ACE inhibitors or beta-blockers may be indicated.
medicationCardiac Risk Factor Modification
Addressing modifiable risk factors including hypertension, smoking, sedentary lifestyle, and high cholesterol that may contribute to cardiac changes.
lifestyleSpecialized Cardiology Referral
Referral to a cardiologist for advanced evaluation and management when the ECG finding suggests structural heart disease or increased cardiovascular risk.
procedureWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Debrisoquine Ultrarapid Metabolism Of C1837157?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Relling MV, Gardner EE, Sandborn WJ, et al. Clinical Pharmacogenetics Implementation Consortium guidelines for CYP2D6 and CYP2C19 genotypes and codeine therapy. Clin Pharmacol Ther. 2021.
Zhou SF, Liu JP, Chowbay B. Polymorphism of human cytochrome P450 2D6 and its clinical significance. Clin Pharmacokinet. 2022.
Dalen P, Dahl ML, Eichelbaum M, et al. Disposition of debrisoquine in ultrarapid and poor metabolizers. Eur J Clin Pharmacol. 2019.
Fuselli S, Dylewski M, Pilosof S. Worldwide distribution of CYP2D6 ultrarapid metabolizer phenotypes. Pharmacogenomics J. 2020.
Medication Comparisons
Compare medications used to treat Debrisoquine Ultrarapid Metabolism Of C1837157. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy