Developmental And Epileptic Encephalopathy 72 C5193063
A severe genetic epilepsy syndrome causing early-onset seizures and significant developmental delay in infants. Treatment focuses on seizure control and supportive care.
Key facts at a glance
- ICD-10
- G40.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Epileptic seizures
Dystonia
Generalized symptoms
(neurologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Global developmental delay
(neurologic)Progressive spasticity
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Broad-Spectrum Antiseizure Medications
Empiric use of broad-spectrum ASMs that address multiple seizure types commonly seen in developmental encephalopathies. Response evaluation guides ongoing management.
Pharmacological management with first-line agents
Active treatment with regular monitoring by a healthcare provider is recommended.
Additional treatment options
Classic Ketogenic Diet
Rigid ketogenic diet protocol with precise macronutrient ratios calculated by metabolic team. May provide significant seizure reduction in refractory cases.
dietaryVagus Nerve Stimulation (VNS)
Surgical implantation of device providing intermittent vagal stimulation to reduce seizure frequency and severity. Parameter adjustments optimize therapeutic benefit.
procedureNeuroimaging Follow-up
Periodic MRI or CT imaging to assess structural changes, rule out secondary causes of deterioration, and evaluate for surgical candidacy.
monitoringRespite Care and Caregiver Support Services
Structured respite services providing temporary care relief for primary caregivers, along with support groups and educational resources.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Developmental And Epileptic Encephalopathy 72 C5193063?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
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Medically reviewed by WellAlly Editorial Team Last reviewed August 26, 2026. · Read our editorial policy