Distal Hereditary Motor Neuropathy Type 7 C4749653
A progressive inherited nerve disorder causing weakness and wasting of muscles, typically starting in the hands and feet. It usually develops in adulthood and worsens over time. Treatment focuses on supportive care and maintaining function.
Key facts at a glance
- ICD-10
- G43.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Respiratory muscle weakness
Foot drop
(neurologic)Generalized symptoms
(neurologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Distal lower limb weakness
(neurologic)Hand muscle atrophy
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Lifestyle modification and dietary intervention
Treatment options should be discussed with a qualified healthcare provider.
Motor neuron disease Physical Therapy
Specialized physical therapy focusing on muscle strengthening, endurance preservation, and compensatory strategies to maintain mobility and prevent deconditioning in hereditary motor neuropathy.
Assistive Device Provision
Assessment and provision of appropriate assistive devices such as ankle-foot orthoses, walking aids, or wheelchairs to maintain mobility and prevent falls.
Additional treatment options
Disease Progression Monitoring
Regular neurological assessments, strength testing, and functional evaluations to track disease progression and adjust management strategies accordingly.
monitoringRespiratory Function Surveillance
Monitoring of respiratory muscle function including vital capacity measurements and sleep studies, as distal HMN can affect respiratory muscles in some cases.
complementaryPsychological Support and Peer Connection
Mental health support addressing anxiety, depression, and adjustment to living with a progressive neurological condition, including connection with support groups.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Distal Hereditary Motor Neuropathy Type 7 C4749653?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Brennan KM, Baiapate L, Rossor AM. Clinical practice guidelines for inherited peripheral neuropathies. Neurology. 2022.
Rossi D, De Grandis D, Pareyson D. Distal hereditary motor neuropathies: a comprehensive review. Neuromuscular Disorders. 2021.
Houlden H, Laura M, Ginsberg L. Clinical and genetic features of distal hereditary motor neuropathy type 7. Brain. 2020.
Scriba CL, Zuchner S. Molecular genetics of distal hereditary motor neuropathy type 7. Journal of Neurology. 2019.
Medication Comparisons
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy