Dock2 Deficiency C4225328
An immune deficiency disorder that affects infection-fighting cells. People with this condition experience recurrent infections. Treatment involves infection prevention and immune system support.
Key facts at a glance
- ICD-10
- D89.9
- ICD-11
- 3A00.0
- Body system
- immunologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Interstitial lung disease
Early-onset combined immunodeficiency with recurrent viral infections
(immunologic)Generalized symptoms
(immunologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Persistent lymphopenia
(hematologic)Autoimmune hepatitis
(hepatobiliary)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Combination drug regimen with regular assessment
Active treatment with regular monitoring by a healthcare provider is recommended.
Immunoglobulin Replacement Therapy
Regular intravenous or subcutaneous immunoglobulin infusions to compensate for deficient antibody production and provide passive immunity against infections.
Prophylactic Antibiotics
Long-term antibiotic prophylaxis to prevent bacterial infections common in primary immunodeficiencies, particularly respiratory tract infections.
Additional treatment options
Infection Surveillance
Regular monitoring of infection frequency, inflammatory markers, and immune function through laboratory testing to adjust treatment protocols.
monitoringInfection Prevention Measures
Implementation of hygiene practices including hand washing, avoiding sick contacts, and mask use during high-risk periods to minimize infection exposure.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Dock2 Deficiency C4225328?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
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View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy