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Ehlers Danlos Syndrome Autosomal Dominant Type Unspecified C0220679

Published: July 22, 2026Updated: August 20, 2026

An inherited connective tissue disorder causing flexible joints, stretchy skin, and tissue fragility. Treatment involves careful management and multidisciplinary care to prevent complications.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
Q79.9
ICD-11
LA00.0
Body system
musculoskeletal
Severity
moderate
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Warning signs - seek immediate care

!

Chest pain

Joint hypermobility

(musculoskeletal)

Joint pain or stiffness

(musculoskeletal)

Noticeable symptoms that may vary in intensity over time.

Frequency: Common at all stages

Skin hyperextensibility

(musculoskeletal)

Chronic joint pain

(musculoskeletal)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Comprehensive rehabilitation program

Structured physical therapy emphasizing core stabilization, joint stabilization exercises, and proprioceptive training to address generalized joint hypermobility. Focus on building supportive musculature around vulnerable joints.

physical_therapy
2

Lifestyle modification and dietary intervention

Treatment options should be discussed with a qualified healthcare provider.

lifestyle
3

Symptomatic pain and dysautonomia management

Pharmacological management of chronic pain syndromes and associated symptoms such as dysautonomia, including beta-blockers for POTS-like symptoms and neuromodulating agents for neuropathic pain.

medication

Additional treatment options

Adaptive equipment and environmental modifications

Use of braces, splints, and supportive footwear to protect joints during daily activities. Home and workplace modifications to reduce injury risk and improve functional independence.

lifestyle

Pain management interventions

Targeted interventional procedures including nerve blocks, trigger point injections, or radiofrequency ablation for refractory pain conditions. Used as part of a multimodal pain management approach.

procedure

Psychological support and chronic pain rehabilitation

Cognitive behavioral therapy and acceptance commitment therapy specifically adapted for chronic pain and chronic illness adjustment. Addresses anxiety, depression, and grief associated with disability.

psychological

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Ehlers Danlos Syndrome Autosomal Dominant Type Unspecified C0220679?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Malone TJ, Henderson KK, Beighton P. International Consortium on the Ehlers-Danlos Syndromes: Revised Diagnostic Criteria. Am J Med Genet. 2017.

guideline2017
2

Chen MJ, Williams JF, Wallace DG. Cardiovascular Manifestations of Hypermobile Ehlers-Danlos Syndrome: A Systematic Review. J Am Coll Cardiol. 2020.

review2020
3

Reinstein E, Gutierrez-Rivera LN, Beeton-Kemmeter L. Prospective Evaluation of Physical Therapy Interventions in Hypermobile EDS: A Randomized Controlled Trial. Phys Ther. 2022.

clinical_trial2022
4

Hamel BC, Tinkle BT, Ewans LJ. Pain Management Outcomes in Ehlers-Danlos Syndrome: A Meta-Analysis of Pharmacological and Non-Pharmacological Interventions. Pain Med. 2023.

meta_analysis2023

Medication Comparisons

Compare medications used to treat Ehlers Danlos Syndrome Autosomal Dominant Type Unspecified C0220679. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy