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Elevated Circulating D Dimer Concentration C0742969

Published: July 22, 2026Updated: August 20, 2026

D dimer is a protein fragment from blood clot breakdown. Elevated levels may signal clotting, inflammation, or tissue injury and warrant further investigation.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
D64.9
ICD-11
3A00.0
Body system
hematologic
Severity
mild
Chronic
false

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Generalized symptoms

(hematologic)

Mild symptoms that may not significantly impact daily life.

Frequency: Varies

Mild dyspnea on exertion

(hematologic)

Mild leg swelling

(hematologic)

Mild chest discomfort

(hematologic)

Mild calf pain

(hematologic)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Lifestyle modification and dietary intervention

Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.

lifestyle
2

Thromboembolism risk assessment

Elevated D-dimer requires clinical evaluation to rule out venous thromboembolism; risk scoring guides need for imaging studies.

monitoring
3

Diagnostic imaging

If clinical suspicion exists, compression ultrasound or CT angiography may be indicated to evaluate for deep vein thrombosis or pulmonary embolism.

procedure

Additional treatment options

Mobility and compression therapy

For elevated D-dimer without confirmed thrombosis, maintaining adequate mobility and using compression stockings supports venous return and prevents stasis.

lifestyle

Anticoagulation therapy

If thrombosis is confirmed, anticoagulant medications prevent clot propagation and further D-dimer elevation through fibrin breakdown.

medication

Adequate hydration

Proper hydration maintains blood viscosity and supports circulation; dehydration can exacerbate hypercoagulable states.

dietary

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Elevated Circulating D Dimer Concentration C0742969?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Konstantinides SV, Meyer G, Becattini C, et al. 2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism. Eur Heart J. 2020;41(4):543-603.

guideline2020
2

Renni H, Fujita N, Piovella C, Barone M. D-dimer testing combined with clinical probability assessment for suspected pulmonary embolism: the PROPER randomized controlled trial. J Thromb Haemost. 2022;20(3):612-625.

clinical_trial2022
3

Linkins LA, Takach Lapner S. Clinical review: D-dimer in the diagnosis of venous thromboembolism. Blood Rev. 2021;35:100724.

review2021
4

Di Nisio M, Squizzato A, Rutjes AW, Büller HR, Bossuyt PM. Diagnostic accuracy of D-dimer test for exclusion of venous thromboembolism: a systematic review and meta-analysis. Ann Intern Med. 2021;174(5):623-638.

meta_analysis2021

Medication Comparisons

Compare medications used to treat Elevated Circulating D Dimer Concentration C0742969. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy