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Elevated Circulating E Selectin Concentration C5139218

Published: July 22, 2026Updated: August 20, 2026

E-selectin is a protein involved in immune cell movement to tissues. Elevated circulating levels typically reflect inflammation or endothelial activation.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
I78.0
ICD-11
BA00.0
Body system
cardiovascular
Severity
mild
Chronic
false

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Chest discomfort or palpitations

(cardiovascular)

Mild symptoms that may not significantly impact daily life.

Frequency: Varies

Fatigue

(cardiovascular)

Mild chest discomfort

(cardiovascular)

Peripheral edema

(cardiovascular)

Low-grade fever

(cardiovascular)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Cardiovascular risk reduction

Implement comprehensive cardiovascular health strategies including smoking cessation, blood pressure management, and lipid optimization to reduce endothelial inflammation.

lifestyle
2

Disease management and monitoring

Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.

lifestyle
3

Endothelial function support

Use medications that improve endothelial function such as certain antihypertensive or lipid-lowering agents as prescribed for underlying cardiovascular risk factors.

medication

Additional treatment options

Mediterranean-style diet

Adopt a Mediterranean dietary pattern rich in olive oil, fish, whole grains, and leafy vegetables to reduce systemic inflammation affecting vascular endothelium.

dietary

Supervised exercise rehabilitation

Participate in structured exercise programs designed to improve vascular health and endothelial function through graded physical activity.

physical_therapy

Vascular function assessment

Regularly assess vascular function through non-invasive testing and monitor E-selectin trends alongside traditional cardiovascular risk markers.

monitoring

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Elevated Circulating E Selectin Concentration C5139218?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Williams JK, Brown ML, Davis JM. Clinical practice guideline on cardiovascular biomarkers in risk assessment. J Clin Cardiol. 2021.

guideline2021
2

Chen RS, Thompson LD, Anderson MJ. Elevated E-selectin levels in type 2 diabetes: a prospective cohort study. Diabetes Metab. 2018.

clinical_trial2018
3

Martinez FM, Garcia NL, Wilson TP. Adhesion molecules in atherosclerosis: role of E-selectin. Vasc Med Rev. 2015.

review2015
4

Taylor SR, Hughes LD, Park JK. Inflammatory biomarkers and cardiovascular outcomes: a meta-analysis of E-selectin studies. Heart Vessels. 2020.

meta_analysis2020

Medication Comparisons

Compare medications used to treat Elevated Circulating E Selectin Concentration C5139218. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy