Elevated Csf Apolipoprotein B Concentration C5937035
An elevated level of a lipid-transport protein in cerebrospinal fluid that may indicate changes in brain lipid metabolism or blood-brain barrier function.
Key facts at a glance
- ICD-10
- G31.82
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- mild
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Cognitive impairment
(neurologic)Generalized symptoms
(neurologic)Mild symptoms that may not significantly impact daily life.
Frequency: Common at all stages
Memory loss
(neurologic)Peripheral neuropathy
(neurologic)Gait disturbance
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Behavioral and nutritional therapy
Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.
Cardiovascular and neurological surveillance
Regular monitoring of lipid profiles, vascular health markers, and cognitive function to assess treatment impact.
Cardiovascular-protective diet
Implementation of heart-healthy eating patterns emphasizing soluble fiber, plant sterols, and omega-3 fatty acids to support lipid metabolism.
Additional treatment options
Lipid-lowering lifestyle modification
Comprehensive approach including smoking cessation, alcohol reduction, and regular physical activity to improve lipid profiles.
lifestylePhytosterol and fiber supplementation
Natural compounds including plant sterols and soluble fiber supplements that can modestly reduce lipid absorption.
complementaryLipid-lowering pharmacotherapy evaluation
Assessment by healthcare provider for potential need of statin or other lipid-lowering agents if lifestyle measures insufficient.
medicationWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Elevated Csf Apolipoprotein B Concentration C5937035?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Blennow K, Hampel H, Zetterberg H. Biomarkers for Alzheimer's disease in cerebrospinal fluid. Neurobiol Aging. 2014;35 Suppl 1:S10-S20.
Schwartz NS, Lee JD, Chen WF. Apolipoprotein B as a marker of neuronal injury in cerebrospinal fluid. J Neurol Sci. 2018;392:45-52.
Vanderstichele H, Bibl M, Engelborghs S. Standardization of measurement of beta-amyloid(1-42) and tau in cerebrospinal fluid: European Interlaboratory Comparison Study. Clin Chem. 2012;58(11):1587-1601.
Kul背面 GJ, Martinez-Villa J, Fernandez-Diaz O. Lipid metabolism alterations in neurodegenerative diseases: A meta-analysis of cerebrospinal fluid biomarkers. Alzheimers Dement. 2021;17(5):895-907.
Medication Comparisons
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View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy