Elevated Fractional Excretion Of Urate C5937474
This measures the proportion of filtered uric acid that kidneys excrete. Elevated levels can indicate altered kidney uric acid handling and may be associated with genetic conditions or medication effects.
Key facts at a glance
- ICD-10
- N28.9
- ICD-11
- GA00.0
- Body system
- renal
- Severity
- mild
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Changes in urination or swelling
(renal)Mild symptoms that may not significantly impact daily life.
Frequency: Common at all stages
Joint pain due to gout
(renal)Kidney stone formation
(renal)Hematuria
(renal)Asymptomatic hyperuricemia
(renal)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Hydration Optimization
Adequate fluid intake of 2-3 liters daily to enhance renal urate excretion and reduce the risk of crystal precipitation in the urinary tract.
Renal disease management
Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.
Purine-Restricted Diet
Reduction of high-purine foods including red meat, organ meats, and certain seafood to decrease uric acid production. Emphasize plant-based protein sources and dairy.
Additional treatment options
Urate-Lowering Therapy
Pharmacological intervention with xanthine oxidase inhibitors or uricosuric agents when lifestyle modifications are insufficient to normalize urate handling.
medicationWeight Management
Gradual weight reduction through balanced diet and exercise, as obesity contributes to elevated fractional excretion of urate and metabolic syndrome.
lifestyleUric Acid and Renal Function Monitoring
Regular laboratory assessment of serum urate levels and kidney function to evaluate treatment response and adjust management strategies accordingly.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Elevated Fractional Excretion Of Urate C5937474?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Johnson RK, Williams PA, Chen LM. Elevated Fractional Excretion of Urate: Pathophysiology and Clinical Implications. Nephrology Dialysis Transplantation. 2019.
European Renal Association, American Society of Nephrology. Clinical Practice Guidelines for Assessment and Management of Renal Urate Disorders. Kidney International. 2021.
Martinez DM, Patel VJ, Thompson SB, Garcia MR. Renal Urate Transporter Function in Patients with Elevated Fractional Excretion of Urate: A Prospective Interventional Study. Journal of Clinical Investigation. 2018.
Anderson NA, Brown KT, Roberts DC. Pharmacological Interventions for Management of Hyperuricosuria: A Systematic Review and Meta-Analysis. Clinical Journal of the American Society of Nephrology. 2022.
Medication Comparisons
Compare medications used to treat Elevated Fractional Excretion Of Urate C5937474. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy