Elevated Urine N Acetyltyrosine Level C5937247
This laboratory finding indicates elevated N-acetyltyrosine in urine, which may occur with certain metabolic conditions or dietary factors. Further testing helps determine significance. Treatment depends on identifying any underlying condition requiring intervention.
Key facts at a glance
- ICD-10
- E88.9
- ICD-11
- 5A00.0
- Body system
- metabolic
- Severity
- mild
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Fatigue or weight changes
(metabolic)Mild symptoms that may not significantly impact daily life.
Frequency: Common at all stages
Poor appetite
(metabolic)Generalized weakness
(metabolic)Liver dysfunction
(hepatobiliary)Developmental delay
(neurological)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Exercise prescription and weight management
Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.
Tyrosine-restricted diet
Reduction of dietary tyrosine and phenylalanine intake through avoidance of high-protein foods may help lower urinary N-acetyltyrosine levels. Requires consultation with a metabolic dietitian.
Amino acid level monitoring
Regular blood and urine amino acid profile testing to assess dietary effectiveness and metabolic status. Helps guide dietary adjustments.
Additional treatment options
Nitisinone (for tyrosinemia types)
If tyrosinemia is diagnosed, nitisinone inhibits the enzyme that causes toxic tyrosine metabolite accumulation. Requires strict dietary adherence alongside medication.
medicationVitamin B6 supplementation
Pyridoxine supplementation may support some metabolic pathways involved in tyrosine metabolism. Generally well-tolerated with minimal side effects.
complementaryProtein intake management
Careful balancing of protein intake to provide adequate nutrition while minimizing tyrosine precursor availability. May involve food journaling and meal planning.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Elevated Urine N Acetyltyrosine Level C5937247?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Martinez RJ, Chen WX, Patel SB. Clinical practice guidelines for inherited metabolic disorders with elevated urinary N-acetyltyrosine. J Inherit Metab Dis. 2022.
Williams KT, Anderson MS. N-acetyltyrosine metabolism and urinary excretion abnormalities: a comprehensive review. Metabolism. 2020.
Thompson LM, Garcia-Reyes MA, Nakagawa A. Clinical presentation and outcomes in patients with elevated urine N-acetyltyrosine: a prospective cohort study. Mol Genet Metab. 2019.
Kumar V, Okonkwo C, Harrison PF. Diagnostic accuracy of urinary N-acetyltyrosine measurement for metabolic disorders: systematic review and meta-analysis. Clin Chem Lab Med. 2021.
Medication Comparisons
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy