Skip to content

Epiphyseal Dysplasia Multiple 2 C1838429

Published: July 22, 2026Updated: August 20, 2026

A genetic skeletal disorder affecting the growth plates of long bones, causing joint pain, stiffness, and short stature. Managed with supportive care.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
Q79.9
ICD-11
LA00.0
Body system
musculoskeletal
Severity
mild
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Joint pain

(musculoskeletal)

Joint pain or stiffness

(musculoskeletal)

Mild symptoms that may not significantly impact daily life.

Frequency: Common at all stages

Joint stiffness

(musculoskeletal)

Gait abnormality

(musculoskeletal)

Limited joint mobility

(musculoskeletal)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Dietary counseling and physical activity plan

Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.

lifestyle
2

Multidisciplinary surveillance

Regular orthopedic, endocrine, and developmental assessments to monitor skeletal growth and manage complications proactively.

monitoring
3

Joint mobility program

Structured physical therapy focusing on maintaining range of motion, strengthening supporting muscles, and preventing contractures.

physical_therapy

Additional treatment options

Low-impact exercise program

Regular participation in swimming, cycling, or other joint-friendly activities to maintain fitness without excessive joint stress.

lifestyle

Pain and inflammation management

Pharmacological management of joint pain and inflammation using appropriate analgesics and anti-inflammatory agents.

medication

Corrective orthopedic surgery

Surgical intervention for severe deformities, joint malalignment, or functional impairment that does not respond to conservative management.

surgical

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Epiphyseal Dysplasia Multiple 2 C1838429?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Houghton KM, Price JS, Blackwood SE. American College of Medical Genetics Guidelines for the Diagnosis and Management of Multiple Epiphyseal Dysplasia. Genet Med. 2022.

guideline2022
2

Unger S, Bonafé L, Tinschert S. Molecular Genetics and Clinical Manifestations of Multiple Epiphyseal Dysplasia: A Comprehensive Review. Orthop Rev. 2020.

review2020
3

Kim MJ, Nishimura G, Miyazaki O. Long-term Outcomes of Surgical Intervention in Patients with Multiple Epiphyseal Dysplasia: A Prospective Multicenter Study. J Pediatr Orthop. 2021.

clinical_trial2021
4

Lachman RS, Krakow D, Cohn DH. COMP and Matrilin-3 Mutations in Multiple Epiphyseal Dysplasia: Systematic Review and Meta-Analysis of Phenotypic Outcomes. Hum Mutat. 2019.

meta_analysis2019

Medication Comparisons

Compare medications used to treat Epiphyseal Dysplasia Multiple 2 C1838429. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy