Fanconi Anemia Complementation Group Q C3808988
A rare genetic disorder affecting DNA repair, causing bone marrow failure and increased cancer risk. Management includes supportive care and stem cell transplant for eligible patients.
Key facts at a glance
- ICD-10
- D61.03
- ICD-11
- 3A00.0
- Body system
- hematologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Bone marrow failure
(hematologic)Generalized symptoms
(hematologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Fatigue
(hematologic)Renal anomalies
(hematologic)Congenital heart defect
(hematologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Combination drug regimen with regular assessment
Active treatment with regular monitoring by a healthcare provider is recommended.
Eltrombopag for Thrombocytopenia
Thrombopoietin receptor agonist that stimulates platelet production in bone marrow failure. May reduce bleeding complications and decrease transfusion requirements in selected patients with cytopenias.
Annual Comprehensive Assessment
Systematic evaluation of hematological, oncological, endocrine, renal, and developmental parameters. Multidisciplinary review enables early detection of emerging complications and treatment adjustment.
Additional treatment options
Orthopedic Intervention for Limb Abnormalities
Surgical management of radial ray defects, thumb abnormalities, and skeletal malformations common in Fanconi Anemia. Procedures may include reconstruction, stabilization, and prosthetic considerations.
surgicalSun Protection and UV Avoidance
Strict photoprotection including broad-spectrum sunscreen, protective clothing, and sun avoidance. Patients with Fanconi Anemia have heightened sensitivity to DNA-damaging agents including UV radiation.
lifestyleIron Chelation Therapy When Indicated
Management of iron overload from chronic transfusions using iron chelating agents. Prevents cardiac, hepatic, and endocrine complications of iron accumulation in vital organs.
dietaryWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Fanconi Anemia Complementation Group Q C3808988?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalMedication Comparisons
Compare medications used to treat Fanconi Anemia Complementation Group Q C3808988. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy