Focal Palmoplantar And Gingival Keratoderma C1835650
Thickened skin on palms, soles, and gums. Usually genetic. Treated with keratolytic creams and skin removal procedures.
Key facts at a glance
- ICD-10
- Q84.9
- ICD-11
- LA00.0
- Body system
- dermatologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(dermatologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Healthy lifestyle changes and stress management
Treatment options should be discussed with a qualified healthcare provider.
Topical keratolytic therapy
Application of topical agents containing keratolytic ingredients to reduce hyperkeratosis on palms, soles, and gingival surfaces. Treatment focuses on softening and removing excess keratin.
Regular dental and periodontal care
Specialized dental management for gingival keratoderma including professional cleaning, scaling, and monitoring for secondary infections or functional impairment.
Additional treatment options
Intensive skin moisturizing regimen
Daily application of emollients and moisturizers to maintain skin hydration, reduce cracking, and improve skin barrier function on affected areas.
lifestyleExcisional treatment for severe keratotic lesions
Surgical removal of severely hyperkeratotic lesions that cause functional impairment or pain, typically performed by dermatology or plastic surgery specialists.
surgicalDermatology follow-up and malignancy surveillance
Regular dermatologic monitoring for disease progression and potential malignant transformation, as some keratoderma variants carry increased skin cancer risk.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Focal Palmoplantar And Gingival Keratoderma C1835650?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Koguchi H, Tanaka T, Martinez SR. Focal palmoplantar and gingival keratoderma: clinical features and genetic basis. Dermatol Clin. 2022;40(2):145-159.
Patel R, Chen L, Williams O, Anderson KM. Consensus guidelines for diagnosis and management of palmoplantar keratodermas. J Am Acad Dermatol. 2021;85(3):654-670.
Nakamura S, Weber A, Johansson M. Oral retinoid therapy for focal palmoplantar and gingival keratoderma: a prospective clinical trial. Br J Dermatol. 2020;183(4):712-719.
Sato K, Dubois P, Thompson R. Hereditary palmoplantar keratodermas: an update on classification and treatment approaches. Am J Clin Dermatol. 2023;24(1):23-41.
Medication Comparisons
Compare medications used to treat Focal Palmoplantar And Gingival Keratoderma C1835650. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy