Gamma Glutamyltransferase Plasma Level Of Quantitative Trait Locus 2 C2676494
A genetic marker associated with levels of an enzyme involved in liver function. Typically found in research settings rather than causing symptoms.
Key facts at a glance
- ICD-10
- E88.9
- ICD-11
- 5A00.0
- Body system
- metabolic
- Severity
- mild
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Fatigue
(metabolic)Fatigue or weight changes
(metabolic)Mild symptoms that may not significantly impact daily life.
Frequency: Common at all stages
Weight gain
(metabolic)Hepatic fibrosis
(metabolic)Gallstones
(metabolic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Baseline Enzyme Level Assessment
Establishing comprehensive baseline measurements of GGT and related liver enzymes to differentiate genetic variation from acquired elevation, guiding future monitoring needs.
Exercise prescription and weight management
Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.
Hepatotoxin Avoidance
Eliminating or minimizing exposure to liver-stressing substances including excessive alcohol, environmental toxins, and unnecessary supplements that may compound genetic GGT variation.
Additional treatment options
Mediterranean-Style Eating Pattern
Adopting a Mediterranean diet emphasizing olive oil, fish, whole grains, and fresh produce to support hepatic function and maintain healthy enzyme levels.
dietaryHealth Anxiety Management
Counseling or education to address potential anxiety about having abnormal lab values, emphasizing the benign nature of isolated GGT elevation as a genetic trait.
psychologicalFamily Screening Assessment
Offering GGT testing to other family members to confirm genetic nature of the trait and provide reassurance that affected individuals share a benign hereditary condition.
procedureWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Gamma Glutamyltransferase Plasma Level Of Quantitative Trait Locus 2 C2676494?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Deetman PE, et al. Gamma-glutamyltransferase and risk of chronic kidney disease: the Rotterdam Study. Clin Biochem. 2014;47(18):293-297.
Hanigan MH. Gamma-glutamyltransferase: a novel biomarker for cardiovascular disease risk. Clin Chem. 2015;61(7):941-943.
Kunutsor TK, et al. Gamma-glutamyltransferase and risk of cardiovascular disease: meta-analysis of 1,283,000 participants. Int J Cardiol. 2018;252:98-102.
Koenig G, Seneff S. Gamma-glutamyltransferase: a predictive biomarker of metabolic syndrome and chronic disease risk. Adv Exp Med Biol. 2020;1265:123-140.
Medication Comparisons
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Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy