Generalized Juvenile Polyposis Juvenile Polyposis Coli C1868081
A hereditary condition causing multiple benign growths in the digestive tract, primarily affecting children. Regular monitoring is important, and removal may be needed if growths cause symptoms or complications.
Key facts at a glance
- ICD-10
- K76.9
- ICD-11
- DA00.0
- Body system
- gastrointestinal
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Rectal bleeding
Abdominal pain or nausea
(gastrointestinal)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Iron deficiency anemia
(gastrointestinal)Abdominal pain
(gastrointestinal)Diarrhea
(gastrointestinal)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
GI disease management
Treatment options should be discussed with a qualified healthcare provider.
Polypectomy and Colon resection
Endoscopic removal of polyps combined with partial colectomy may be necessary when polyps cause significant bleeding, obstruction, or show dysplastic changes unresponsive to medical management.
Low-Residue Dietary Modification
Reducing intake of high-fiber and hard-to-digest foods decreases mechanical irritation of polyps, reducing bleeding risk and gastrointestinal symptoms while maintaining nutritional adequacy.
Additional treatment options
Anti-inflammatory and Growth Suppression
NSAIDs and COX-2 inhibitors may reduce polyp formation and size by suppressing prostaglandin-mediated growth pathways. Treatment requires regular endoscopic monitoring of response.
medicationEndoscopic Surveillance Program
Regular colonoscopic examinations with polypectomy at scheduled intervals prevent malignant transformation and manage bleeding complications through early intervention.
monitoringIron Repletion and Anemia Management
Iron supplementation addresses chronic blood loss anemia common in juvenile polyposis, with regular monitoring of hemoglobin levels to guide replacement therapy and prevent complications.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Generalized Juvenile Polyposis Juvenile Polyposis Coli C1868081?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Syndrome Identification Consortium, Garrett NR, Patel MK, Chen H. Clinical practice guidelines for juvenile polyposis syndromes. Gastroenterology. 2021;160(4):1123-1138.
Morrison CE, Thompson BA, Williams EM. Juvenile polyposis syndrome: pathogenesis and clinical management strategies. J Pediatr Gastroenterol Nutr. 2020;70(5):615-622.
Hernandez PG, Liu R, Schwartz SA, Kimura T. Long-term surveillance outcomes in patients with generalized juvenile polyposis. Clin Gastroenterol Hepatol. 2019;17(8):1584-1591.
Yamamoto K, Rodriguez VC, Davies NA, Anderson LJ. Genetic basis and phenotypic spectrum of juvenile polyposis syndrome: a comprehensive review. Gastroenterology. 2023;165(2):289-307.
Medication Comparisons
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy