Grade V Vesicoureteral Reflux C3274340
A severe condition where urine flows backward from the bladder to the kidneys, potentially causing infections and kidney damage. Usually diagnosed in children, it may require surgical correction.
Key facts at a glance
- ICD-10
- N39.0
- ICD-11
- GA00.0
- Body system
- genitourinary
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Fever with chills
Flank pain
Generalized symptoms
(genitourinary)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Recurrent urinary tract infections
(genitourinary)Hematuria
(genitourinary)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Medication management with follow-up
Active treatment with regular monitoring by a healthcare provider is recommended.
Ureteral Reimplantation Surgery
Surgical correction to reconstruct the ureterovesical junction and create a proper anti-reflux mechanism, typically performed using open or laparoscopic techniques.
Deflux Injection
Minimally invasive endoscopic injection of dextranomer/hyaluronic acid bulking agent into the ureteral opening to create a valve mechanism preventing reflux.
Additional treatment options
Prophylactic Antibiotics
Low-dose daily or alternating-day antibiotics such as trimethoprim-sulfamethoxazole or nitrofurantoin to prevent urinary tract infections while awaiting surgical correction.
medicationRenal Function Surveillance
Regular monitoring of kidney function through serum creatinine, blood pressure measurement, and imaging to assess for kidney damage progression.
monitoringBladder Training and Voiding Hygiene
Scheduled voiding routines and proper toileting posture to reduce bladder pressure and minimize residual urine that could contribute to reflux episodes.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Grade V Vesicoureteral Reflux C3274340?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalMedication Comparisons
Compare medications used to treat Grade V Vesicoureteral Reflux C3274340. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy