Growth Restriction Hypoplastic Kidneys Alopecia And Distinctive Facies C5543375
A rare genetic syndrome causing poor growth before birth, underdeveloped kidneys, hair loss, and unique facial features. Management focuses on kidney function monitoring and supportive care.
Key facts at a glance
- ICD-10
- Q89.9
- ICD-11
- LA00.0
- Body system
- other
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(other)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Growth delay
(endocrine)Alopecia
(integumentary)Facial dysmorphism
(craniofacial)Renal hypoplasia
(renal)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Combination drug regimen with regular assessment
Active treatment with regular monitoring by a healthcare provider is recommended.
Renal function surveillance and management
Regular assessment of kidney function through serum creatinine, BUN, and ultrasound monitoring of kidney size and structure. Management of hypertension and proteinuria associated with renal involvement.
Nutritional support and growth optimization
Calorie-dense nutritional supplementation supports growth restriction. Protein intake optimization and micronutrient supplementation address specific deficiencies. Feeding support may be needed for oral intake difficulties.
Additional treatment options
Management of associated complications
Pharmacological management of hypertension, renal complications, and any associated endocrine abnormalities. Coordination with specialists for complex medication regimens addressing multiple organ systems.
medicationDermatological care for alopecia
Management of hair loss with gentle hair care practices, protection from sun exposure, and psychological support. Wigs or head coverings may be recommended for cosmetic concerns and sun protection.
lifestyleGenetic evaluation and genetic counseling
Comprehensive genetic testing and counseling to confirm diagnosis, understand prognosis, and inform family planning decisions. Discussion of recurrence risks and available prenatal testing options.
surgicalWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Growth Restriction Hypoplastic Kidneys Alopecia And Distinctive Facies C5543375?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalMedication Comparisons
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy