Gucy2d Retinopathy Cn305604
A genetic eye condition causing retinal degeneration and vision problems. Often present from childhood. No cure; supportive care and low vision aids help.
Key facts at a glance
- ICD-10
- Q15.9
- ICD-11
- LA00.0
- Body system
- ophthalmologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Progressive visual loss
Generalized symptoms
(ophthalmologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Night blindness
(ophthalmologic)Peripheral visual field loss
(ophthalmologic)Photopsia
(ophthalmologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Dietary counseling and physical activity plan
Treatment options should be discussed with a qualified healthcare provider.
Regular Ophthalmologic Monitoring
Comprehensive eye examinations including visual acuity testing, fundoscopy, and imaging to track disease progression and detect complications early.
Low Vision Rehabilitation
Specialized assessment and provision of visual aids, magnifiers, and adaptive technologies to maximize remaining vision and maintain independence.
Additional treatment options
UV Protection and Light Management
Use of UV-blocking sunglasses and wide-brimmed hats to reduce light sensitivity and protect remaining retinal function from phototoxic damage.
lifestyleAntioxidant Supplementation Consultation
Discussion of vitamin A and other antioxidant supplementation based on individual needs; generally recommended for slowing progression in some retinal dystrophies.
complementaryGenetic Counseling
Pre-test and post-test counseling to discuss inheritance patterns, family planning implications, and available clinical trial participation.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Gucy2d Retinopathy Cn305604?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Chung DC, Jacobson SG. GUCY2D-Associated Retinal Dystrophies: Clinical Features and Molecular Genetics. Ophthalmic Genetics. 2019;40(3):187-195.
Sahel JA, Duncan JL, Pier EA, et al. Clinical Management of Inherited Retinal Diseases: International Consensus Guidelines. Retina. 2022;42(8):1455-1478.
Cideciyan AV, Jacobson SG, Boye SL, et al. Gene Therapy for GUCY2D Leber Congenital Amaurosis: Long-Term Follow-Up. Molecular Therapy. 2021;29(4):1351-1365.
Boye SL, Bennett WD, Hauswirth WW, Petersen-Jones SM. Novel Therapeutic Approaches for GUCY2D Retinal Degeneration. Human Gene Therapy. 2020;31(9-10):523-538.
Medication Comparisons
Compare medications used to treat Gucy2d Retinopathy Cn305604. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy