Hdac3 Related Neurodevelopmental Disorder Cn380229
A neurodevelopmental disorder caused by changes in a gene important for brain development, leading to intellectual disability and developmental delays. Treatment involves speech, occupational, and physical therapy.
Key facts at a glance
- ICD-10
- G40.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Seizures
Generalized symptoms
(neurologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Intellectual disability
(neurologic)Speech delay
(neurologic)Behavioral abnormalities
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Applied behavior analysis therapy
Structured behavioral intervention programs targeting communication, social, and adaptive skill development through systematic reinforcement strategies and skill training protocols.
Targeted drug therapy with dose adjustment
Active treatment with regular monitoring by a healthcare provider is recommended.
Additional treatment options
Management of comorbid behavioral symptoms
Pharmacological approaches to address hyperactivity, impulsivity, anxiety, or aggression when behavioral interventions alone are insufficient. Medication selection is individualized based on symptom profile and comorbidities.
medicationMotor skill development program
Therapeutic exercises and activities to address developmental coordination difficulties, improve gross and fine motor skills, and enhance functional independence in daily activities.
physical_therapyCardiac evaluation and surveillance
Baseline and periodic cardiac assessments including echocardiography given association with congenital heart defects in some HDAC3-related disorder cases. Ongoing monitoring for structural or functional abnormalities.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Hdac3 Related Neurodevelopmental Disorder Cn380229?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalMedication Comparisons
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View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy