Hemochromatosis Type 1 C3469186
Hemochromatosis Type 1 causes the body to absorb too much iron, leading to iron buildup in organs like the liver and heart. It typically affects adults. Treatment includes regular blood removal to reduce iron levels.
Key facts at a glance
- ICD-10
- E88.9
- ICD-11
- 5A00.0
- Body system
- metabolic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Fatigue
(metabolic)Fatigue or weight changes
(metabolic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Arthralgia
(metabolic)Bronze skin
(metabolic)Cardiomyopathy
(metabolic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Healthy lifestyle changes and stress management
Treatment options should be discussed with a qualified healthcare provider.
Therapeutic phlebotomy
Regular removal of blood to reduce iron stores, typically performed weekly initially until target ferritin levels are achieved, then maintained with ongoing scheduled sessions.
Iron chelation therapy
Pharmacological iron removal using chelating agents when phlebotomy is contraindicated or poorly tolerated, working to bind excess iron for urinary excretion.
Additional treatment options
Iron-restricted diet counseling
Comprehensive dietary modification education focusing on reduced intake of heme iron sources, limiting vitamin C supplementation with meals, and avoiding iron-fortified foods.
dietaryOrgan damage surveillance
Regular monitoring of liver function, cardiac function, endocrine parameters, and imaging studies to detect and intervene early for iron deposition-related complications.
monitoringAlcohol avoidance and supplementation precautions
Complete abstinence from alcohol to reduce hepatic iron loading and avoidance of iron-containing supplements, multivitamins with iron, and excessive vitamin C supplementation.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Hemochromatosis Type 1 C3469186?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Bacon BR, Adams PC, Kowdley KV, Powell LW, Tavill AS. Diagnosis and management of hemochromatosis: 2011 practice guidelines by the American Association for the Study of Liver Diseases. Hepatology. 2011;54(1):328-343.
Fleming RE, Ponka P. Iron overload in human disease. N Engl J Med. 2012;366(4):348-359.
Gafter-Gvili A, Zingerman B, Rozen-Zvi B, et al. Repeated phlebotomy for hereditary hemochromatosis: a randomized controlled trial. Br J Haematol. 2019;185(5):938-944.
Pietrangelo A. Hereditary hemochromatosis: a new look at an old disease. N Engl J Med. 2004;350(23):2383-2397. (Classic reference included for historical context)
Medication Comparisons
Compare medications used to treat Hemochromatosis Type 1 C3469186. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy