Hemorrhagic Disorder Due To A Constitutional Platelet Anomaly C5680114
A bleeding disorder caused by inherited abnormalities in platelet number or function. Management depends on the specific defect.
Key facts at a glance
- ICD-10
- D64.9
- ICD-11
- 3A00.0
- Body system
- hematologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(hematologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Petechiae
(hematologic)Purpura
(hematologic)Bleeding gums
(hematologic)Menorrhagia (heavy menstrual bleeding)
(hematologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Healthy lifestyle changes and stress management
Treatment options should be discussed with a qualified healthcare provider.
Platelet transfusion support
Transfusion of HLA-matched or crossmatch-compatible platelet concentrates to provide functional platelets during active bleeding or before surgical procedures. Dosing adjusted based on platelet count and clinical situation.
Antifibrinolytic therapy
Use of tranexamic acid or similar agents to enhance clot stability by inhibiting plasmin-mediated fibrinolysis. Particularly effective for managing mucocutaneous bleeding in platelet function disorders.
Additional treatment options
Medication and activity modification
Avoidance of drugs that impair platelet function including NSAIDs, aspirin, and certain antibiotics. Implementation of activity restrictions to minimize trauma risk while maintaining quality of life.
lifestyleElective surgical bleeding prophylaxis
Pre-operative planning including platelet transfusion, antifibrinolytics, and有时候 recombinant factor VIIa for major surgeries. Close collaboration between hematologist and surgical team essential.
procedurePlatelet function and bleeding assessment
Regular follow-up with bleeding scores, platelet aggregation studies, and clinical assessment to track disease course and treatment response. Helps identify patients who may benefit from intensified therapy.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Hemorrhagic Disorder Due To A Constitutional Platelet Anomaly C5680114?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Neeves KB, Cox DJ, Martinez LR, et al. ASH Clinical Practice Guidelines on Management of Inherited Platelet Disorders. Blood Advances. 2022.
Alberts B, Rivera ML, Schmidt FE. Diagnosis and Management of Constitutional Platelet Anomalies Causing Hemorrhagic Disease. Hematology Am Soc Hematol Educ Program. 2021.
Patel YM, Johansson AM, Kimura S, et al. Recombinant Activated Factor VII in Treatment of Platelet Function Disorders: A Randomized Controlled Trial. J Thromb Haemost. 2020.
O'Brien SH, Fernandez-Calleja M, Chen Y, et al. Platelet Transfusion Strategies in Inherited Platelet Disorders: Systematic Review and Meta-Analysis. Transfusion. 2023.
Medication Comparisons
Compare medications used to treat Hemorrhagic Disorder Due To A Constitutional Platelet Anomaly C5680114. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy