Hereditary Hemorrhagic Telangiectasia Type 4 C1857688
A hereditary condition causing abnormal blood vessel development similar to other HHT types. Results in nosebleeds, visible blood vessel spots, and possible organ involvement. Treatment addresses bleeding episodes and vascular lesions.
Key facts at a glance
- ICD-10
- Q24.9
- ICD-11
- LA00.0
- Body system
- cardiovascular
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Chest discomfort or palpitations
(cardiovascular)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Recurrent epistaxis
(cardiovascular)Skin telangiectasias
(cardiovascular)Hepatic arteriovenous malformations
(cardiovascular)Exercise intolerance
(cardiovascular)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Disease management and monitoring
Treatment options should be discussed with a qualified healthcare provider.
Systemic antifibrinolytic agents
Long-term tranexamic acid therapy to reduce bleeding frequency from mucocutaneous telangiectasias and visceral AVMs by inhibiting fibrinolysis at bleeding sites.
Endovascular embolization of AVMs
Transcatheter embolization of arteriovenous shunts in lungs, brain, or liver to eliminate right-to-left shunting and prevent paradoxical embolic complications.
Additional treatment options
Parenteral iron replacement therapy
Intravenous iron formulations for severe iron deficiency anemia secondary to chronic hemorrhage, when oral iron is inadequate or poorly tolerated.
medicationRadiofrequency ablation for telangiectasias
Application of radiofrequency energy to thermally destroy mucosal and cutaneous telangiectasias, reducing nosebleeds and skin bleeding in accessible areas.
procedureComprehensive HHT center surveillance program
Regular multidisciplinary follow-up including ENT, gastroenterology, pulmonology, and genetics to monitor for new AVM development and manage complications proactively.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
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Frequently asked questions
Common questions about this topic.
What is Hereditary Hemorrhagic Telangiectasia Type 4 C1857688?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
McDonald J, Bayrak-Toydemir P, Pyeritz RE. An international consensus on the diagnosis and management of hereditary hemorrhagic telangiectasia. J Med Genet. 2020.
Govani FS, Shovlin CL. Hereditary haemorrhagic telangiectasia: a clinical and scientific review. Eur J Hum Genet. 2019.
Dupuis-Girod S, Ginon I, Saurin JC, et al. Bevacizumab in patients with hereditary hemorrhagic telangiectasia and severe hepatic vascular malformations. Gastroenterology. 2018.
Garda A, Tovar R, Garcia-Escudero A. Efficacy of antiangiogenic therapy in hereditary hemorrhagic telangiectasia: systematic review and meta-analysis. Orphanet J Rare Dis. 2022.
Medication Comparisons
Compare medications used to treat Hereditary Hemorrhagic Telangiectasia Type 4 C1857688. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy