Hereditary Spastic Paraplegia 62 C4284588
A rare inherited disorder causing progressive spastic paraplegia with variable symptoms. Treatment focuses on physical therapy, anti-spasticity medications, and supportive measures to maintain function.
Key facts at a glance
- ICD-10
- G11.4
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(neurologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Spastic gait disturbance
(neurologic)Lower limb muscle weakness
(neurologic)Urinary urgency
(neurologic)Mild cognitive impairment
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Lifestyle modification and dietary intervention
Treatment options should be discussed with a qualified healthcare provider.
Structured Physiotherapy Protocol
Individualized physiotherapy focusing on progressive stretching, balance training, and functional exercises to preserve mobility and reduce spasticity-related complications. Consistency and long-term adherence are critical for optimal outcomes.
Spasticity Management Pharmacotherapy
Pharmacological management using oral antispasmodic agents to decrease muscle tone and improve functional abilities. Response to medication varies among individuals and requires careful monitoring.
Additional treatment options
Botulinum Toxin Injections
Localized injections of botulinum toxin into specific overactive muscles to temporarily reduce focal spasticity. Effects typically last 3-4 months and can facilitate participation in physical therapy.
procedureMobility Aids and Assistive Devices
Provision and training with appropriate assistive devices such as ankle-foot orthoses, walking aids, or wheelchairs as needed to maintain independence and prevent falls.
lifestylePsychological Support and Counseling
Psychological counseling and support services to address the emotional impact of living with a chronic progressive condition. Includes coping strategies, family education, and connection to support groups.
psychologicalMedication Comparisons
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View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy