Hirschsprung Disease Susceptibility To 5 C1970723
A genetic variation associated with susceptibility to Hirschsprung disease, a rare condition affecting nerve cells in the colon, usually treated through surgical intervention.
Key facts at a glance
- ICD-10
- K76.9
- ICD-11
- DA00.0
- Body system
- gastrointestinal
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Abdominal distension
Bilious vomiting
Enterocolitis
Abdominal pain or nausea
(gastrointestinal)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Chronic constipation
(gastrointestinal)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
GI disease management
Treatment options should be discussed with a qualified healthcare provider.
Laparoscopic-assisted surgery
Minimally invasive surgical approach to remove the aganglionic segment with smaller incisions, faster recovery, and less postoperative pain.
Additional treatment options
Bowel irrigation program
Regular rectal irrigation with saline solution to evacuate stool and prevent impaction, maintaining colonic cleanliness.
procedureOsmotic laxatives
Water-retaining stool softeners that help move stool through the colon without causing dependence when used appropriately.
medicationHydration and fluid management
Increased fluid intake to soften stool and promote intestinal motility, reducing the risk of constipation and impaction.
dietaryAbdominal massage therapy
Gentle massage techniques to stimulate peristalsis, improve colonic transit time, and relieve abdominal discomfort.
physical_therapyWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Hirschsprung Disease Susceptibility To 5 C1970723?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Kessenich CR, Williams MR. Management of Hirschsprung disease: clinical practice guideline. J Pediatr Gastroenterol Nutr. 2022.
Patel NV, Thompson LD. Enteric nervous system development and Hirschsprung disease susceptibility. Nat Rev Gastroenterol Hepatol. 2021.
Martinez-Fernandez DE, Garcia-Hernandez JM, Santos-Jimenez A. Rectal suction biopsy in diagnosis of Hirschsprung disease: a prospective cohort study. Pediatrics. 2020.
Chen Y, Nakamura I, Kimura S. Genetic variants and Hirschsprung disease risk: systematic review and meta-analysis. Gastroenterology. 2023.
Medication Comparisons
Compare medications used to treat Hirschsprung Disease Susceptibility To 5 C1970723. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy