Hyperinsulinemic Hypoglycemia Familial 3 C1865290
An inherited disorder causing the pancreas to release excess insulin, leading to dangerously low blood sugar levels. It often appears in infancy and may require medication, special diets, or surgery.
Key facts at a glance
- ICD-10
- E34.9
- ICD-11
- 5A00.0
- Body system
- endocrine
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Fatigue or weight changes
(endocrine)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Diazoxide Oral Suspension
Benzothiadiazine derivative that opens ATP-sensitive potassium channels on pancreatic beta cells, directly inhibiting insulin release and maintaining blood glucose homeostasis.
Endocrine management
Active treatment with regular monitoring by a healthcare provider is recommended.
Glycemic Index Modified Diet
Customized nutrition plan using low glycemic index foods to provide sustained energy release, reducing insulin demand and preventing reactive hypoglycemia.
Additional treatment options
Ambulatory Glucose Profile Analysis
Continuous glucose monitoring data interpreted through standardized algorithms to identify patterns, guide therapy adjustments, and optimize glycemic control.
monitoringNear-Total Pancreatectomy
Extensive pancreatic resection removing 85-95% of pancreatic tissue when diffuse disease fails to respond to maximal medical therapy and diet modifications.
surgicalAcupuncture Adjunctive Therapy
Traditional Chinese medicine technique potentially modulating autonomic nervous system function and improving hypoglycemic awareness in select patients.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Hyperinsulinemic Hypoglycemia Familial 3 C1865290?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy