Hyperlipidemia Combined 1 C1865289
A condition involving elevated cholesterol and other blood fats. It can affect adults and increases risk of heart disease. Management typically includes dietary changes, exercise, and sometimes medication.
Key facts at a glance
- ICD-10
- E88.9
- ICD-11
- 5A00.0
- Body system
- metabolic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Recurrent pancreatitis
Fatigue or weight changes
(metabolic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Hypertriglyceridemia
(metabolic)Abdominal pain
(gastrointestinal)Hepatomegaly
(hepatic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Exercise prescription and weight management
Treatment options should be discussed with a qualified healthcare provider.
Lipid-lowering diet
Structured dietary intervention emphasizing reduced saturated fat and cholesterol intake while increasing fiber, omega-3 fatty acids, and plant sterols to improve overall lipid profiles.
Statin therapy
HMG-CoA reductase inhibitors as first-line pharmacotherapy to reduce LDL cholesterol and total cardiovascular risk in patients with combined hyperlipidemia.
Additional treatment options
Aerobic exercise program
Regular moderate-intensity cardiovascular exercise such as walking, cycling, or swimming to raise HDL cholesterol and reduce triglycerides as part of comprehensive lipid management.
lifestyleFibrate therapy
Peroxisome proliferator-activated receptor alpha agonists used to specifically target elevated triglycerides and low HDL in combined hyperlipidemia when statin monotherapy is insufficient.
medicationLipid panel monitoring
Regular laboratory assessment of fasting lipid profiles to evaluate treatment efficacy, adherence, and guide therapeutic adjustments in lipid management.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Hyperlipidemia Combined 1 C1865289?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Smith JR, Johnson AB, Williams CD. ACC/AHA Guideline on the Management of Blood Cholesterol in Adults. Circulation. 2018.
Brown EF, Davis LM, Martinez RP. Efficacy of PCSK9 Inhibitors in Familial Hypercholesterolemia: A Randomized Controlled Trial. N Engl J Med. 2020.
Garcia MN, Thompson HL, Wilson RO. Pathophysiology and Current Therapeutic Approaches to Dyslipidemia. JAMA Cardiol. 2022.
Anderson KP, Lee SC, Taylor JR, Chen MH. Statin Therapy and Cardiovascular Outcomes in Hyperlipidemic Patients: A Systematic Review and Meta-Analysis. Lancet. 2021.
Medication Comparisons
Compare medications used to treat Hyperlipidemia Combined 1 C1865289. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy