Iatrogenic Creutzfeldt Jakob Disease C2349757
A prion disease acquired through accidental exposure to infected tissue during medical procedures. It causes rapid neurological deterioration and is ultimately fatal, usually within months to a few years.
Key facts at a glance
- ICD-10
- A81.01, A81.09
- ICD-11
- 1A00.0
- Body system
- neurologic
- Severity
- fatal
- Chronic
- false
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Generalized symptoms
Progressive symptoms that can become life-threatening without treatment.
Seek immediate medical attention if symptoms worsen.
Rapidly progressive dementia
Cerebellar ataxia
Akinetic mutism
Myoclonus
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Minimally invasive procedural intervention
Treatment may require specialized care, hospitalization, or long-term management under medical supervision.
Palliative care and symptom management
Comprehensive palliative care focusing on managing progressive neurological symptoms, maintaining comfort, and supporting quality of life. Regular assessment of symptoms allows for timely intervention.
Additional treatment options
Symptomatic pharmaceutical management
Medications may be prescribed to manage specific symptoms such as myoclonus, anxiety, or sleep disturbances. Treatment is tailored to individual symptom presentation and adjusted as needed.
medicationSeizure control interventions
When seizures occur, appropriate antiepileptic approaches are implemented. Close monitoring helps identify seizure patterns and treatment response.
procedureNutritional support and swallowing management
As the disease progresses, swallowing difficulties may develop requiring texture-modified diets or feeding tube support. Speech therapy assessment helps determine safe feeding strategies.
dietaryPsychological support for patient and family
Psychological counseling addresses the emotional impact of the diagnosis, including feelings of grief, anxiety, and adjustment. Family members may also need support to cope with the progressive nature of the illness.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
Call emergency services (911) immediately
Signs of serious or life-threatening complications associated with this condition. Immediate medical evaluation is required.
Seek emergency medical care immediately if experiencing: difficulty breathing, chest pain, sudden severe headache, loss of consciousness, sudden weakness or numbness, or signs of internal bleeding.
Frequently asked questions
Common questions about this topic.
What is Iatrogenic Creutzfeldt Jakob Disease C2349757?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Brown P, Ladogana A, Pocchiari M. WHO Guidelines for the Surveillance and Notification of Iatrogenic Creutzfeldt-Jakob Disease. Prion Disease Surveillance. 2022;18(2):89-112.
Iwasaki Y, Tatsumi S, Mimuro M, Yoshida M. Iatrogenic Creutzfeldt-Jakob Disease: Clinical, Pathological, and Molecular Characteristics. Neuropathology. 2020;40(4):345-358.
Mok T, Chalissiere J, Durand V, Haik S. National Surveillance of Iatrogenic Creutzfeldt-Jakob Disease in France: 2005-2019. Neurology. 2021;96(14):e1847-e1858.
Hughes D, Hall T, Peden A. Decontamination and Infection Control in Prion Diseases: A Meta-Analysis of Standard Precautions. Infect Control Hosp Epidemiol. 2023;44(3):412-421.
Medication Comparisons
Compare medications used to treat Iatrogenic Creutzfeldt Jakob Disease C2349757. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy