Immunodeficiency 61 C1845903
A rare genetic disorder affecting immune cells, resulting in vulnerability to frequent and severe infections. Often identified in early childhood. Treatment includes preventive care and immune support.
Key facts at a glance
- ICD-10
- D89.9
- ICD-11
- 3A00.0
- Body system
- immunologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Autoimmune cytopenias
Generalized symptoms
(immunologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Recurrent sinusitis
(immunologic)Pneumonia episodes
(immunologic)Enlarged lymph nodes
(immunologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
High-Dose Immunoglobulin Therapy
Aggressive immunoglobulin replacement targeting higher trough levels to achieve better infection prevention in severe phenotypes. Individualized dosing based on pharmacokinetics and clinical outcomes.
Medication management with follow-up
Active treatment with regular monitoring by a healthcare provider is recommended.
Central Line Maintenance
For patients requiring frequent intravenous therapy, indwelling catheter management with strict aseptic technique. Regular flushing, dressing changes, and monitoring for catheter-related bloodstream infections.
Additional treatment options
Comprehensive Immunologic Profiling
Detailed laboratory assessment including specific antibody responses to vaccines, lymphocyte function tests, and genetic confirmation when indicated. Results guide prognostic counseling and treatment intensification.
monitoringEnteral Nutrition Support
For patients with gastrointestinal involvement, specialized feeding formulas may be necessary to ensure adequate nutrition while minimizing antigen exposure. Nasogastric or gastrostomy feeding considered when oral intake insufficient.
dietaryTonsillectomy Consideration
Surgical removal of hypertrophied lymphoid tissue may be considered in select cases with chronic local infection burden or airway compromise. Careful risk-benefit assessment required given immunologic implications.
surgicalWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Immunodeficiency 61 C1845903?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalMedication Comparisons
Compare medications used to treat Immunodeficiency 61 C1845903. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy