Immunodeficiency 64 C5231402
A rare genetic primary immunodeficiency affecting immune system function, making affected individuals highly susceptible to infections.
Key facts at a glance
- ICD-10
- D89.9
- ICD-11
- 3A00.0
- Body system
- immunologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Severe disseminated viral infection (e.g., CMV disease)
Generalized symptoms
(immunologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Recurrent bacterial infections
(immunologic)Eczema-like skin lesions
(dermatologic)Autoimmune thyroid disease
(endocrine)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Immunoglobulin Replacement Therapy
Regular IVIG or subcutaneous immunoglobulin therapy forms the cornerstone of treatment, providing broad-spectrum antibody coverage and reducing infectious complications.
Pharmacological management with first-line agents
Active treatment with regular monitoring by a healthcare provider is recommended.
Aggressive Infection Management
Prompt initiation of broad-spectrum antimicrobials at first signs of infection, with subsequent narrowing based on culture results, to prevent sepsis and complications.
Additional treatment options
Immunologic Parameter Tracking
Serial measurements of immunoglobulin levels, lymphocyte subsets, and vaccine responses guide therapy adjustments and indicate disease progression or improvement.
monitoringStem Cell Transplant Assessment
Comprehensive evaluation for hematopoietic stem cell transplantation candidacy in patients with severe phenotype or inadequate response to conventional therapy.
procedureNutritional Optimization
High-protein diet with micronutrient supplementation supports immune function and muscle mass maintenance, particularly important during recovery from recurrent infections.
dietaryWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Immunodeficiency 64 C5231402?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalMedication Comparisons
Compare medications used to treat Immunodeficiency 64 C5231402. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy