Immunodeficiency 78 With Autoimmunity And Developmental Delay C5543159
A rare immunodeficiency with autoimmune features and developmental delays. It requires multidisciplinary care addressing both immune dysfunction and developmental needs.
Key facts at a glance
- ICD-10
- D89.9
- ICD-11
- 3A00.0
- Body system
- immunologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Autoimmune hemolytic anemia
Autoimmune hepatitis
Generalized symptoms
(immunologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Recurrent respiratory infections
(respiratory)Global developmental delay
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Immunoglobulin Replacement Therapy
Essential immunoglobulin therapy addressing the immunodeficiency component of this complex disorder.
Targeted drug therapy with dose adjustment
Active treatment with regular monitoring by a healthcare provider is recommended.
Autoimmunity Management
Immunomodulatory medications such as corticosteroids or rituximab to control autoimmune manifestations.
Additional treatment options
Developmental Physical Therapy
Specialized exercises and motor skill training to address developmental delays and improve functional mobility.
physical_therapyNeurodevelopmental Support Services
Comprehensive psychological evaluation and ongoing support for cognitive delays and behavioral concerns.
psychologicalMultidisciplinary Monitoring Program
Coordinated care across immunology, neurology, and developmental specialists with regular assessments.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Immunodeficiency 78 With Autoimmunity And Developmental Delay C5543159?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy