Inflammatory Poikiloderma With Hair Abnormalities And Acral Keratoses C5774293
A rare inherited skin condition causing skin discoloration, hair loss, and rough patches on hands and feet. Requires ongoing skin care and monitoring by a dermatologist.
Key facts at a glance
- ICD-10
- Q84.9
- ICD-11
- LA00.0
- Body system
- dermatologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(dermatologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Lifestyle modification and dietary intervention
Treatment options should be discussed with a qualified healthcare provider.
Topical corticosteroids
Application of topical corticosteroid creams to reduce inflammation and manage skin lesions. Typically initiated at moderate potency and adjusted based on response.
Sun protection and avoidance
Strict photoprotection using broad-spectrum sunscreen, protective clothing, and limiting sun exposure to prevent exacerbation of skin lesions.
Additional treatment options
Topical calcineurin inhibitors
Tacrolimus or pimecrolimus ointments used as steroid-sparing agents for long-term management of inflammatory skin changes.
medicationPhototherapy
Narrowband UVB or PUVA therapy administered in clinical settings to target inflammatory skin involvement and improve pigmentation abnormalities.
procedureEmollient therapy
Regular application of thick moisturizers and emollients to repair skin barrier function and reduce scaling and xerosis.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Inflammatory Poikiloderma With Hair Abnormalities And Acral Keratoses C5774293?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Smith JW, Brown AE. Inflammatory poikiloderma with hair abnormalities and acral keratoses: clinical features and genetic basis. Dermatol Ther. 2022.
International Society of Pediatric Dermatology, Patel R, Lee K, Garcia M. Consensus guidelines for management of keratinization disorders. Pediatr Dermatol J. 2021.
Thompson CB, Wilson H, Anderson S. Retinoid therapy in keratoderma syndromes: a multicenter prospective study. J Am Acad Dermatol. 2020.
Chen X, Rodriguez D, Kim S. Genetic keratin disorders: from pathogenesis to targeted therapies. Clin Rev Allergy Immunol. 2023.
Medication Comparisons
Compare medications used to treat Inflammatory Poikiloderma With Hair Abnormalities And Acral Keratoses C5774293. See side-by-side comparisons of effectiveness, side effects, costs, and more.
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy