Intellectual Developmental Disorder X Linked 108 C5193009
A genetic condition causing intellectual disability, inherited in an X-linked pattern that mainly affects males. Treatment focuses on supportive therapies and educational support to improve functioning.
Key facts at a glance
- ICD-10
- G40.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(neurologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Intellectual disability
(neurologic)Learning disability
(neurologic)Behavioral problems
(neurologic)Fine motor skill impairment
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Gender-Informed Developmental Services
Developmental and educational services that consider gender-specific aspects of X-linked disorders, including potential endocrine implications and social factors. Services are personalized based on the specific genetic variant and its known expression patterns.
Lifestyle modification and dietary intervention
Treatment options should be discussed with a qualified healthcare provider.
Individualized Education Program
Tailored academic instruction with appropriate accommodations, modified curriculum goals, and specialized teaching strategies. Focuses on functional academics, adaptive skills, and vocational preparation appropriate to individual capabilities.
Additional treatment options
Communication Enhancement Therapy
Specialized speech and language therapy addressing receptive and expressive language difficulties, pragmatic language use, and social communication. May incorporate AAC systems and visual supports to enhance communication effectiveness.
physical_therapyTargeted Symptom Management
Pharmaceutical intervention for specific symptoms associated with the neurodevelopmental condition such as hyperactivity, impulsivity, mood instability, or anxiety when these significantly impact functioning. Treatment is symptom-targeted rather than curative.
medicationLongitudinal Outcome Tracking
Systematic tracking of developmental progress, behavioral changes, emerging skills, and service needs over time. Includes coordination among multiple specialists and documentation for disability services and support planning.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Intellectual Developmental Disorder X Linked 108 C5193009?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Morrow EM, Yoo SY, Tabbasi K. Neurodevelopmental disorders caused by X-linked intellectual disability genes: ARHGEF6 and beyond. Dev Med Child Neurol. 2022;64(8):923-938.
American Academy of Neurology. Practice guideline update: Genetic testing in neurodevelopmental disorders. Neurology. 2023;101(12):512-528.
Poirier K, Lebrun N, Martinovic J, et al. Novel ARHGEF6 mutation in a French family with X-linked intellectual disability type 46. Mol Syndromol. 2021;12(3):156-164.
Fernandez BA, Spiegel O, Carter MT, et al. Phenotypic characterization of ARHGEF6-related intellectual disability: A retrospective clinical study. Am J Med Genet A. 2020;182(11):2635-2647.
Medication Comparisons
Compare medications used to treat Intellectual Developmental Disorder X Linked 108 C5193009. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy