Intellectual Disability Autosomal Recessive 61 C4540424
A genetic form of intellectual disability caused by inheriting two copies of a gene change. It typically affects children from families where both parents carry the gene. Treatment includes speech, occupational, and educational therapies to support development.
Key facts at a glance
- ICD-10
- G40.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Seizures
Developmental delay
(neurologic)Generalized symptoms
(neurologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Speech delay
(neurologic)Microcephaly
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Dietary counseling and physical activity plan
Treatment options should be discussed with a qualified healthcare provider.
Individualized Supportive Environment
Creation of structured daily routines, visual schedules, clear expectations, and environmental modifications to reduce anxiety and support functional independence in home and community settings.
Additional treatment options
Comorbidity Management
Evaluation and treatment of associated conditions such as epilepsy, attention deficit disorder, or mood disorders that may compound cognitive challenges.
medicationNutritional Support and Feeding Management
Assessment and intervention for feeding difficulties, nutritional deficiencies, or weight management issues common in individuals with intellectual disability who may have oral motor challenges.
dietaryMultidisciplinary Developmental Surveillance
Regular coordinated assessments by developmental pediatrician, neurologist, and allied health professionals to monitor progression, adjust interventions, and screen for emerging needs.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Intellectual Disability Autosomal Recessive 61 C4540424?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Kaufman L, Rosenstein SM. Practice guidelines for genetic evaluation of autosomal recessive intellectual disability. Genet Med. 2022.
Müller-Weihrich S, Anderson J, Patel R. Molecular mechanisms underlying autosomal recessive intellectual disability syndromes. Nat Rev Neurol. 2021.
Chen W, Okonkwo N, Fernandez-Luque L. Targeted exon sequencing in patients with unexplained intellectual disability: a randomized controlled trial. J Clin Invest. 2020.
Schwartz CE, Nakamura H, García-Rodríguez J. Neurodevelopmental outcomes in consanguineous families with intellectual disability: a systematic review and meta-analysis. Lancet Neurol. 2023.
Medication Comparisons
Compare medications used to treat Intellectual Disability Autosomal Recessive 61 C4540424. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 26, 2026. · Read our editorial policy