Skip to content

Juvenile Primary Lateral Sclerosis C1853396

Published: July 22, 2026Updated: August 27, 2026

A progressive neurological disorder affecting motor nerves, causing muscle stiffness and weakness in children. Treatment focuses on supportive care and mobility support.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 27, 2026Editorial policy

Key facts at a glance

ICD-10
G12.23
ICD-11
8A00.0
Body system
neurologic
Severity
severe
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Generalized symptoms

(neurologic)

Significant symptoms that substantially affect daily functioning.

Frequency: Common at all stages

Spastic gait (stiff, scissor-like gait)

(neurologic)

Hyperreflexia (exaggerated reflexes)

(neurologic)

Dysarthria (slurred speech)

(neurologic)

Pseudobulbar affect (involuntary laughing/crying)

(neurologic)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Intensive Physical Therapy Program

A comprehensive physical therapy regimen focusing on maintaining muscle strength, flexibility, and functional mobility through targeted exercises and stretching protocols.

physical_therapy
2

Pharmacological management with first-line agents

Active treatment with regular monitoring by a healthcare provider is recommended.

medication
3

Symptomatic Motor Neuron Disease Management

Pharmacological management using muscle relaxants and antispasmodic agents to address spasticity and muscle stiffness associated with motor neuron degeneration.

medication

When to seek medical help

Recognize when you need immediate medical attention.

See a doctor within 24 hours

Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.

Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Juvenile Primary Lateral Sclerosis C1853396?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Medication Comparisons

Compare medications used to treat Juvenile Primary Lateral Sclerosis C1853396. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy