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Kidney Leiomyosarcoma C1335743

Published: July 22, 2026Updated: August 20, 2026

A rare, aggressive cancer that develops in the smooth muscle tissue of the kidney. Treatment usually requires surgery and may include chemotherapy or radiation.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
N28.9
ICD-11
GA00.0
Body system
renal
Severity
severe
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Warning signs - seek immediate care

!

Gross hematuria

Changes in urination or swelling

(renal)

Significant symptoms that substantially affect daily functioning.

Frequency: Common at all stages

Flank pain

(renal)

Palpable abdominal mass

(renal)

Unexplained weight loss

(renal)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Renal disease management

Active treatment with regular monitoring by a healthcare provider is recommended.

medication
2

Surgical Resection

Aggressive surgical removal of the tumor with wide margins, potentially including partial or radical nephrectomy and removal of adjacent structures if involved.

surgical
3

Chemotherapy

Systemic chemotherapy using agents effective against soft tissue sarcomas, typically administered in cycles for advanced or high-grade tumors.

medication

Additional treatment options

Radiation Therapy

Localized radiation treatment used before surgery to shrink tumors or after surgery to eliminate residual cancer cells and reduce recurrence risk.

procedure

Immunotherapy

Treatment using drugs that stimulate the immune system to recognize and attack cancer cells, increasingly used for advanced sarcomas.

medication

Palliative and Supportive Care

Comprehensive symptom management and psychosocial support for patients with advanced disease, focusing on quality of life and coping strategies.

psychological

When to seek medical help

Recognize when you need immediate medical attention.

See a doctor within 24 hours

Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.

Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Kidney Leiomyosarcoma C1335743?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Medication Comparisons

Compare medications used to treat Kidney Leiomyosarcoma C1335743. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy