Kidney Transplant Rejection C0238217
The immune system attacks a transplanted kidney, which can occur shortly after or years later. Immunosuppressive medications are used to prevent or manage rejection.
Key facts at a glance
- ICD-10
- N28.9
- ICD-11
- GA00.0
- Body system
- renal
- Severity
- severe
- Chronic
- false
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Decreased urine output
Changes in urination or swelling
(renal)Significant symptoms that substantially affect daily functioning.
Frequency: Varies
Elevated serum creatinine
(renal)Fever
(systemic)Fatigue
(systemic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Immunosuppressive Therapy
Calcineurin inhibitors such as tacrolimus or cyclosporine combined with corticosteroids to suppress the immune response and prevent rejection of the transplanted kidney.
Renal disease management
Active treatment with regular monitoring by a healthcare provider is recommended.
Additional treatment options
Anti-thymocyte Globulin
Monoclonal antibody therapy administered to treat acute cellular rejection episodes by depleting T-lymphocytes and reducing immune-mediated damage to the graft.
medicationTransplant Surveillance Protocol
Regular monitoring of kidney function through serum creatinine, estimated glomerular filtration rate, and protocol biopsies to detect early signs of rejection.
monitoringInfection Prevention Measures
Strict adherence to hand hygiene, food safety practices, and avoidance of crowds during immunosuppressive therapy to minimize infection risk.
lifestylePost-transplant Nutrition
Balanced diet with appropriate protein intake, sodium restriction, and careful management of blood glucose to support kidney function and recovery.
dietaryWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Kidney Transplant Rejection C0238217?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalMedication Comparisons
Compare medications used to treat Kidney Transplant Rejection C0238217. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy